Malignant peripheral nerve sheath tumor of the oral mucosa: Case report and literature review

Background: Malignant peripheral nerve sheath tumor (MPNST) is an uncommon tumor in the head and neck region that develops either from a preexisting neurofibroma or de novo. Observation: We report here a case of MPNST of the buccal mucosa in a 40 years old female whose chief complaint was a recurren...

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Main Authors: Wafaa Mahfoud, Manal Bouya, Mokrane Khazana, Ihsane Ben Yahya
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:Advances in Oral and Maxillofacial Surgery
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2667147623000134
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author Wafaa Mahfoud
Manal Bouya
Mokrane Khazana
Ihsane Ben Yahya
author_facet Wafaa Mahfoud
Manal Bouya
Mokrane Khazana
Ihsane Ben Yahya
author_sort Wafaa Mahfoud
collection DOAJ
description Background: Malignant peripheral nerve sheath tumor (MPNST) is an uncommon tumor in the head and neck region that develops either from a preexisting neurofibroma or de novo. Observation: We report here a case of MPNST of the buccal mucosa in a 40 years old female whose chief complaint was a recurrent painful nodule. The diagnosis is considered as the most elusive and difficult among soft tissue sarcomas because of its non specific presentation, both clinically and pathologically. Conclusion: This clinical case illustrates the challenge of delivering a pertinent diagnosis of MPNST due to its non-specific presentation both clinically and histopathologically. It also emphasizes the importance of a high level of vigilance when assessing painful mucosal lesions of normal aspect.
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spelling doaj.art-7a22654987954a24ba5b89e8e4e5ccc52023-02-19T04:27:43ZengElsevierAdvances in Oral and Maxillofacial Surgery2667-14762023-03-019100401Malignant peripheral nerve sheath tumor of the oral mucosa: Case report and literature reviewWafaa Mahfoud0Manal Bouya1Mokrane Khazana2Ihsane Ben Yahya3Corresponding author.; Department of Medicine and Oral Surgery, Universite Hassan II Casablanca Faculte de Medecine Dentaire, Casablanca, MoroccoDepartment of Medicine and Oral Surgery, Universite Hassan II Casablanca Faculte de Medecine Dentaire, Casablanca, MoroccoDepartment of Medicine and Oral Surgery, Universite Hassan II Casablanca Faculte de Medecine Dentaire, Casablanca, MoroccoDepartment of Medicine and Oral Surgery, Universite Hassan II Casablanca Faculte de Medecine Dentaire, Casablanca, MoroccoBackground: Malignant peripheral nerve sheath tumor (MPNST) is an uncommon tumor in the head and neck region that develops either from a preexisting neurofibroma or de novo. Observation: We report here a case of MPNST of the buccal mucosa in a 40 years old female whose chief complaint was a recurrent painful nodule. The diagnosis is considered as the most elusive and difficult among soft tissue sarcomas because of its non specific presentation, both clinically and pathologically. Conclusion: This clinical case illustrates the challenge of delivering a pertinent diagnosis of MPNST due to its non-specific presentation both clinically and histopathologically. It also emphasizes the importance of a high level of vigilance when assessing painful mucosal lesions of normal aspect.http://www.sciencedirect.com/science/article/pii/S2667147623000134MPNSTMalignant peripheral nerve sheath tumorMalignant schwannomaOral cancerOral oncology
spellingShingle Wafaa Mahfoud
Manal Bouya
Mokrane Khazana
Ihsane Ben Yahya
Malignant peripheral nerve sheath tumor of the oral mucosa: Case report and literature review
Advances in Oral and Maxillofacial Surgery
MPNST
Malignant peripheral nerve sheath tumor
Malignant schwannoma
Oral cancer
Oral oncology
title Malignant peripheral nerve sheath tumor of the oral mucosa: Case report and literature review
title_full Malignant peripheral nerve sheath tumor of the oral mucosa: Case report and literature review
title_fullStr Malignant peripheral nerve sheath tumor of the oral mucosa: Case report and literature review
title_full_unstemmed Malignant peripheral nerve sheath tumor of the oral mucosa: Case report and literature review
title_short Malignant peripheral nerve sheath tumor of the oral mucosa: Case report and literature review
title_sort malignant peripheral nerve sheath tumor of the oral mucosa case report and literature review
topic MPNST
Malignant peripheral nerve sheath tumor
Malignant schwannoma
Oral cancer
Oral oncology
url http://www.sciencedirect.com/science/article/pii/S2667147623000134
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