Domain-Based Functional Improvements in Bipolar Disorder After Interpersonal and Social Rhythm Therapy

BackgroundStudies typically report overall change in function when assessing bipolar disorder (BD) interventions, but individual domains are not analyzed. Which aspects of functioning are impacted is clearly important and may differ between treatments.MethodsData were analyzed from two previous clin...

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Main Authors: William Moot, Marie Crowe, Maree Inder, Kate Eggleston, Christopher Frampton, Richard J. Porter
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Psychiatry
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fpsyt.2022.767629/full
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author William Moot
Marie Crowe
Maree Inder
Kate Eggleston
Christopher Frampton
Richard J. Porter
author_facet William Moot
Marie Crowe
Maree Inder
Kate Eggleston
Christopher Frampton
Richard J. Porter
author_sort William Moot
collection DOAJ
description BackgroundStudies typically report overall change in function when assessing bipolar disorder (BD) interventions, but individual domains are not analyzed. Which aspects of functioning are impacted is clearly important and may differ between treatments.MethodsData were analyzed from two previous clinical trials of Interpersonal and Social Rhythm Therapy (IPSRT) for BD patients. Change in total and subscale scores on the Social Adjustment Scale Self-Report (SAS-SR) from 0 to 78 weeks, were analyzed.Results152 BD patients took part in randomized controlled trials of IPSRT (n = 38) vs. Specialist Supportive Care (SSC) (n = 43), and of IPSRT (n = 41) vs. treatment as usual (TAU) which was discharge to primary care (n = 30). IPSRT was superior to TAU on change in the social and leisure activities and extended family subscales, and SAS-SR total score over 18 months.LimitationsStudies were not designed to be pooled. Patients in study 1 were younger and symptomatic at baseline. Patients assigned to TAU were more likely to drop-out. Patients did not respond to subscales that were not personally applicable (work, marital, children).ConclusionIPSRT had a positive impact on two SAS-SR subscales compared to TAU over 18 months. Other subscales were limited by the lack of respondents due to individual applicability. Different psychotherapy may have differential effects on different domains of function. Measures of function and research into functioning in BD should include domain-based measures, and report the numbers of participants who respond to questions in each domain.
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spelling doaj.art-7a22bb00bd7044d9a7c2fea5ec479f3d2022-12-21T23:44:58ZengFrontiers Media S.A.Frontiers in Psychiatry1664-06402022-02-011310.3389/fpsyt.2022.767629767629Domain-Based Functional Improvements in Bipolar Disorder After Interpersonal and Social Rhythm TherapyWilliam MootMarie CroweMaree InderKate EgglestonChristopher FramptonRichard J. PorterBackgroundStudies typically report overall change in function when assessing bipolar disorder (BD) interventions, but individual domains are not analyzed. Which aspects of functioning are impacted is clearly important and may differ between treatments.MethodsData were analyzed from two previous clinical trials of Interpersonal and Social Rhythm Therapy (IPSRT) for BD patients. Change in total and subscale scores on the Social Adjustment Scale Self-Report (SAS-SR) from 0 to 78 weeks, were analyzed.Results152 BD patients took part in randomized controlled trials of IPSRT (n = 38) vs. Specialist Supportive Care (SSC) (n = 43), and of IPSRT (n = 41) vs. treatment as usual (TAU) which was discharge to primary care (n = 30). IPSRT was superior to TAU on change in the social and leisure activities and extended family subscales, and SAS-SR total score over 18 months.LimitationsStudies were not designed to be pooled. Patients in study 1 were younger and symptomatic at baseline. Patients assigned to TAU were more likely to drop-out. Patients did not respond to subscales that were not personally applicable (work, marital, children).ConclusionIPSRT had a positive impact on two SAS-SR subscales compared to TAU over 18 months. Other subscales were limited by the lack of respondents due to individual applicability. Different psychotherapy may have differential effects on different domains of function. Measures of function and research into functioning in BD should include domain-based measures, and report the numbers of participants who respond to questions in each domain.https://www.frontiersin.org/articles/10.3389/fpsyt.2022.767629/fullbipolar disorderpsychotherapydomain-basedfunctionfunctional improvementsIPSRT
spellingShingle William Moot
Marie Crowe
Maree Inder
Kate Eggleston
Christopher Frampton
Richard J. Porter
Domain-Based Functional Improvements in Bipolar Disorder After Interpersonal and Social Rhythm Therapy
Frontiers in Psychiatry
bipolar disorder
psychotherapy
domain-based
function
functional improvements
IPSRT
title Domain-Based Functional Improvements in Bipolar Disorder After Interpersonal and Social Rhythm Therapy
title_full Domain-Based Functional Improvements in Bipolar Disorder After Interpersonal and Social Rhythm Therapy
title_fullStr Domain-Based Functional Improvements in Bipolar Disorder After Interpersonal and Social Rhythm Therapy
title_full_unstemmed Domain-Based Functional Improvements in Bipolar Disorder After Interpersonal and Social Rhythm Therapy
title_short Domain-Based Functional Improvements in Bipolar Disorder After Interpersonal and Social Rhythm Therapy
title_sort domain based functional improvements in bipolar disorder after interpersonal and social rhythm therapy
topic bipolar disorder
psychotherapy
domain-based
function
functional improvements
IPSRT
url https://www.frontiersin.org/articles/10.3389/fpsyt.2022.767629/full
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