Ameliorative effect of soybean lecithin on the liver enzymes of rats supplemented with high cholesterol
The present experiment was investigated to study the ameliorative role of soybean lecithin specially phosphatidylcholin on liver enzymes (ALT) and (AST) in intact and hypercholesterolemic infected rats.Thirty two adult male rats have been used in this study, were randomly selected and equally divid...
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| Format: | Article |
| Language: | English |
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Faculty of Veterinary Medicine, University of Kufa
2018-06-01
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| Series: | Kufa Journal for Veterinary Medical Sciences |
| Subjects: | |
| Online Access: | https://journal.uokufa.edu.iq/index.php/kjvs/article/view/4095 |
| _version_ | 1797364088948391936 |
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| author | Sarah Mohammed Alshammary Luma Waleed Khaleel |
| author_facet | Sarah Mohammed Alshammary Luma Waleed Khaleel |
| author_sort | Sarah Mohammed Alshammary |
| collection | DOAJ |
| description | The present experiment was investigated to study the ameliorative role of soybean lecithin specially phosphatidylcholin on liver enzymes (ALT) and (AST) in intact and hypercholesterolemic infected rats.Thirty two adult male rats have been used in this study, were randomly selected and equally divided in to four groups as follows C, T1 , T2, T3.They were treated orally (daily) for 42 days as follows; C:control group, were given distilled water by gavage needle, T1: rats of this group were given soybean lecithin only (430mg\kg\day) orally; T2:rats of this groups were given only cholesterol (10gm\day) orally; T3: rats of this groups were given soybean lecithin (430mg\kg\day) orally, and supplemented with high cholesterol (10gm\day) orally within diet.The daily supplementation of soybean lecithin induces a significant decrease (p > 0.05) in liver enzymes (ALT & AST) as compared with (T2) group which has seen remarkable rise in these enzymes respectively. Moreover, the histopathological examination showed results referred that cholesterol effects significantly on the liver cells by causing sever fatty changes characterized by variable size round clear spaces in the hepatocytes. Also, there is a mononuclear cells aggregation in liver parenchyma and congested blood vessels without any fatty vacuoles in (T2).. |
| first_indexed | 2024-03-08T16:30:20Z |
| format | Article |
| id | doaj.art-7a232267b53d4ae19c6e7f82efbca62f |
| institution | Directory Open Access Journal |
| issn | 2077-9798 2959-8478 |
| language | English |
| last_indexed | 2024-03-08T16:30:20Z |
| publishDate | 2018-06-01 |
| publisher | Faculty of Veterinary Medicine, University of Kufa |
| record_format | Article |
| series | Kufa Journal for Veterinary Medical Sciences |
| spelling | doaj.art-7a232267b53d4ae19c6e7f82efbca62f2024-01-06T10:13:15ZengFaculty of Veterinary Medicine, University of KufaKufa Journal for Veterinary Medical Sciences2077-97982959-84782018-06-019110.36326/kjvs/2018/v9i14095Ameliorative effect of soybean lecithin on the liver enzymes of rats supplemented with high cholesterolSarah Mohammed AlshammaryLuma Waleed KhaleelThe present experiment was investigated to study the ameliorative role of soybean lecithin specially phosphatidylcholin on liver enzymes (ALT) and (AST) in intact and hypercholesterolemic infected rats.Thirty two adult male rats have been used in this study, were randomly selected and equally divided in to four groups as follows C, T1 , T2, T3.They were treated orally (daily) for 42 days as follows; C:control group, were given distilled water by gavage needle, T1: rats of this group were given soybean lecithin only (430mg\kg\day) orally; T2:rats of this groups were given only cholesterol (10gm\day) orally; T3: rats of this groups were given soybean lecithin (430mg\kg\day) orally, and supplemented with high cholesterol (10gm\day) orally within diet.The daily supplementation of soybean lecithin induces a significant decrease (p > 0.05) in liver enzymes (ALT & AST) as compared with (T2) group which has seen remarkable rise in these enzymes respectively. Moreover, the histopathological examination showed results referred that cholesterol effects significantly on the liver cells by causing sever fatty changes characterized by variable size round clear spaces in the hepatocytes. Also, there is a mononuclear cells aggregation in liver parenchyma and congested blood vessels without any fatty vacuoles in (T2)..https://journal.uokufa.edu.iq/index.php/kjvs/article/view/4095ALTASTCholesterolHypercholesterolemiaSoybean lecithin |
| spellingShingle | Sarah Mohammed Alshammary Luma Waleed Khaleel Ameliorative effect of soybean lecithin on the liver enzymes of rats supplemented with high cholesterol Kufa Journal for Veterinary Medical Sciences ALT AST Cholesterol Hypercholesterolemia Soybean lecithin |
| title | Ameliorative effect of soybean lecithin on the liver enzymes of rats supplemented with high cholesterol |
| title_full | Ameliorative effect of soybean lecithin on the liver enzymes of rats supplemented with high cholesterol |
| title_fullStr | Ameliorative effect of soybean lecithin on the liver enzymes of rats supplemented with high cholesterol |
| title_full_unstemmed | Ameliorative effect of soybean lecithin on the liver enzymes of rats supplemented with high cholesterol |
| title_short | Ameliorative effect of soybean lecithin on the liver enzymes of rats supplemented with high cholesterol |
| title_sort | ameliorative effect of soybean lecithin on the liver enzymes of rats supplemented with high cholesterol |
| topic | ALT AST Cholesterol Hypercholesterolemia Soybean lecithin |
| url | https://journal.uokufa.edu.iq/index.php/kjvs/article/view/4095 |
| work_keys_str_mv | AT sarahmohammedalshammary ameliorativeeffectofsoybeanlecithinontheliverenzymesofratssupplementedwithhighcholesterol AT lumawaleedkhaleel ameliorativeeffectofsoybeanlecithinontheliverenzymesofratssupplementedwithhighcholesterol |