C1q/TNF‐related peptide 8 (CTRP8) promotes temozolomide resistance in human glioblastoma

C1q/TNF‐related peptide 8 (CTRP8) promotes temozolomide resistance in human glioblastoma

The C1q/TNF‐related peptide 8 (CTRP8) has recently emerged as a novel ligand of the G protein‐coupled receptor RXFP1 in the fatal brain tumor glioblastoma (GBM). We previously demonstrated that the CTRP8‐RXFP1 ligand–receptor system promotes motility and matrix invasion of patient GBM and U87 MG cel...

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Bibliographic Details
Main Authors: Thatchawan Thanasupawat, Aleksandra Glogowska, Maxwell Burg, Jerry Krcek, Jason Beiko, Marshall Pitz, Guo‐Jun Zhang, Sabine Hombach‐Klonisch, Thomas Klonisch
Format: Article
Language:English
Published: Wiley 2018-09-01
Series:Molecular Oncology
Subjects:
alkylating drug
base excision repair
CTRP8
DNA damage repair
MPG
RXFP1
Online Access:https://doi.org/10.1002/1878-0261.12349

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