Renalase Protects the Cardiomyocytes of Sprague-Dawley Rats Against Ischemia and Reperfusion Injury by Reducing Myocardial Cell Necrosis and Apoptosis

Renalase Protects the Cardiomyocytes of Sprague-Dawley Rats Against Ischemia and Reperfusion Injury by Reducing Myocardial Cell Necrosis and Apoptosis

Background/Aims: Renalase, a novel flavoprotein expressed in the kidney and heart, reduces renal tubular necrosis and apoptosis, which suggests that it might protect against necrosis and/or apoptosis in myocardial ischemia reperfusion injury (MIRI). The present study thus explored the effects of ren...

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Bibliographic Details
Main Authors: Xiaogang Li, Zijian Xie, Minyuan Lin, Ruixia Huang, Zhongshu Liang, Wei Huang, Weihong Jiang
Format: Article
Language:English
Published: Karger Publishers 2015-05-01
Series:Kidney & Blood Pressure Research
Subjects:
Ischemia and reperfusion injury
Lentivirus
RNA interference
Recombinant renalase protein
Renalase
Online Access:http://www.karger.com/Article/FullText/368497

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