Novel canonical and non-canonical viral antigens extend current targets for immunotherapy of HPV-driven cervical cancer

Novel canonical and non-canonical viral antigens extend current targets for immunotherapy of HPV-driven cervical cancer

Summary: Current immunotherapeutic approaches for human papillomavirus (HPV)-driven cervical cancer target the viral oncogenes E6 and E7. We report viral canonical and alternative reading frame (ARF)-derived sequences presented on cervical tumor cells, including antigens encoded by the conserved vir...

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Bibliographic Details
Main Authors: Xu Peng, Isaac Woodhouse, Gemma Hancock, Robert Parker, Kristina Marx, Julius Müller, Silvia Salatino, Thomas Partridge, Annalisa Nicastri, Hanqing Liao, Gary Kruppa, Karin Hellner, Lucy Dorrell, Nicola Ternette
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:iScience
Subjects:
Immunology
Cell biology
Cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223001785

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http://www.sciencedirect.com/science/article/pii/S2589004223001785

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