Intestinal Flora-Derived Kynurenic Acid Protects Against Intestinal Damage Caused by Candida albicans Infection via Activation of Aryl Hydrocarbon Receptor

Intestinal Flora-Derived Kynurenic Acid Protects Against Intestinal Damage Caused by Candida albicans Infection via Activation of Aryl Hydrocarbon Receptor

Colonization of the intestinal tract by Candida albicans (C. albicans) can lead to invasive candidiasis. Therefore, a functional intestinal epithelial barrier is critical for protecting against invasive C. albicans infections. We collected fecal samples from patients with Candida albicans bloodstrea...

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Bibliographic Details
Main Authors: Zetian Wang, Liping Yin, Yue Qi, Jiali Zhang, Haiyan Zhu, Jianguo Tang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Microbiology
Subjects:
intestinal flora
invasive C. albicans infections
aryl hydrocarbon receptor
kynurenic acid
intestinal barrier function
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2022.934786/full

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