Diminished Value Discrimination in Obsessive-Compulsive Disorder: A Prospect Theory Model of Decision-Making Under Risk
Introduction: It has been hypothesized that people diagnosed with anxiety and obsessive-compulsive disorder (OCD) exhibit behavioral aberrations when faced with the potential for negative outcomes, but the specific cognitive aspects of decision-making that may be altered have not been systematically...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2019-07-01
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| Series: | Frontiers in Psychiatry |
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| Online Access: | https://www.frontiersin.org/article/10.3389/fpsyt.2019.00469/full |
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| author | Sophie A. George Sophie A. George Sophie A. George Jony Sheynin Jony Sheynin Richard Gonzalez Israel Liberzon Israel Liberzon James L. Abelson |
| author_facet | Sophie A. George Sophie A. George Sophie A. George Jony Sheynin Jony Sheynin Richard Gonzalez Israel Liberzon Israel Liberzon James L. Abelson |
| author_sort | Sophie A. George |
| collection | DOAJ |
| description | Introduction: It has been hypothesized that people diagnosed with anxiety and obsessive-compulsive disorder (OCD) exhibit behavioral aberrations when faced with the potential for negative outcomes, but the specific cognitive aspects of decision-making that may be altered have not been systematically studied in clinical populations. Here, we studied decision-making in a clinical cohort using a task that allows for examination of the decision weights and values associated with different choice outcomes.Methods: Patients diagnosed with OCD (n = 10), generalized anxiety disorder (n = 15), social anxiety disorder (n = 14), and healthy controls (n = 20) were given a decision-making task and choices were modeled using a cumulative prospect theory framework.Results: We found OCD patients to have lower value discrimination than controls, as well as less optimal performance on the task, an effect that was mostly driven by trials with only positive outcomes.Discussion: Our results shed light on the cognitive processes that drive altered decision-making under risk in OCD. Specifically, they demonstrate that OCD patients have diminished sensitivity to positive outcomes, which might be associated with risk aversion and altered learning of gain. These findings also extend prior reports, suggesting that altered cognitive processing during decision-making is linked to altered perception of value, but not probability, in these patients. |
| first_indexed | 2024-12-12T06:37:43Z |
| format | Article |
| id | doaj.art-7a360d015ca74d4bbb4ff226d70a863d |
| institution | Directory Open Access Journal |
| issn | 1664-0640 |
| language | English |
| last_indexed | 2024-12-12T06:37:43Z |
| publishDate | 2019-07-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Psychiatry |
| spelling | doaj.art-7a360d015ca74d4bbb4ff226d70a863d2022-12-22T00:34:26ZengFrontiers Media S.A.Frontiers in Psychiatry1664-06402019-07-011010.3389/fpsyt.2019.00469458162Diminished Value Discrimination in Obsessive-Compulsive Disorder: A Prospect Theory Model of Decision-Making Under RiskSophie A. George0Sophie A. George1Sophie A. George2Jony Sheynin3Jony Sheynin4Richard Gonzalez5Israel Liberzon6Israel Liberzon7James L. Abelson8Veterans Affairs Ann Arbor Healthcare System, Ann Arbor, MI, United StatesDepartment of Psychiatry, University of Michigan, Ann Arbor, MI, United StatesDepartment of Social and Behavioral Sciences, Dixie State University, St George, UT, United StatesVeterans Affairs Ann Arbor Healthcare System, Ann Arbor, MI, United StatesDepartment of Psychiatry, University of Michigan, Ann Arbor, MI, United StatesDepartment of Psychology, University of Michigan, Ann Arbor, MI, United StatesVeterans Affairs Ann Arbor Healthcare System, Ann Arbor, MI, United StatesDepartment of Psychiatry, University of Michigan, Ann Arbor, MI, United StatesDepartment of Psychiatry, University of Michigan, Ann Arbor, MI, United StatesIntroduction: It has been hypothesized that people diagnosed with anxiety and obsessive-compulsive disorder (OCD) exhibit behavioral aberrations when faced with the potential for negative outcomes, but the specific cognitive aspects of decision-making that may be altered have not been systematically studied in clinical populations. Here, we studied decision-making in a clinical cohort using a task that allows for examination of the decision weights and values associated with different choice outcomes.Methods: Patients diagnosed with OCD (n = 10), generalized anxiety disorder (n = 15), social anxiety disorder (n = 14), and healthy controls (n = 20) were given a decision-making task and choices were modeled using a cumulative prospect theory framework.Results: We found OCD patients to have lower value discrimination than controls, as well as less optimal performance on the task, an effect that was mostly driven by trials with only positive outcomes.Discussion: Our results shed light on the cognitive processes that drive altered decision-making under risk in OCD. Specifically, they demonstrate that OCD patients have diminished sensitivity to positive outcomes, which might be associated with risk aversion and altered learning of gain. These findings also extend prior reports, suggesting that altered cognitive processing during decision-making is linked to altered perception of value, but not probability, in these patients.https://www.frontiersin.org/article/10.3389/fpsyt.2019.00469/fullobsessive-compulsive disorderdecision-makingprospect theoryrisk aversionpositive outcome |
| spellingShingle | Sophie A. George Sophie A. George Sophie A. George Jony Sheynin Jony Sheynin Richard Gonzalez Israel Liberzon Israel Liberzon James L. Abelson Diminished Value Discrimination in Obsessive-Compulsive Disorder: A Prospect Theory Model of Decision-Making Under Risk Frontiers in Psychiatry obsessive-compulsive disorder decision-making prospect theory risk aversion positive outcome |
| title | Diminished Value Discrimination in Obsessive-Compulsive Disorder: A Prospect Theory Model of Decision-Making Under Risk |
| title_full | Diminished Value Discrimination in Obsessive-Compulsive Disorder: A Prospect Theory Model of Decision-Making Under Risk |
| title_fullStr | Diminished Value Discrimination in Obsessive-Compulsive Disorder: A Prospect Theory Model of Decision-Making Under Risk |
| title_full_unstemmed | Diminished Value Discrimination in Obsessive-Compulsive Disorder: A Prospect Theory Model of Decision-Making Under Risk |
| title_short | Diminished Value Discrimination in Obsessive-Compulsive Disorder: A Prospect Theory Model of Decision-Making Under Risk |
| title_sort | diminished value discrimination in obsessive compulsive disorder a prospect theory model of decision making under risk |
| topic | obsessive-compulsive disorder decision-making prospect theory risk aversion positive outcome |
| url | https://www.frontiersin.org/article/10.3389/fpsyt.2019.00469/full |
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