Toxigenic Properties of <i>Yersinia enterocolitica</i> Biotype 1A
<i>Yersinia (Y.) enterocolitica</i>, an etiological agent of yersiniosis, is a bacterium whose pathogenicity is determined, among other things, by its ability to produce toxins. The aim of this article was to present the most important toxins that are produced by biotype 1A strains of &l...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-02-01
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| Series: | Toxins |
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| Online Access: | https://www.mdpi.com/2072-6651/14/2/118 |
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| author | Aleksandra Platt-Samoraj |
| author_facet | Aleksandra Platt-Samoraj |
| author_sort | Aleksandra Platt-Samoraj |
| collection | DOAJ |
| description | <i>Yersinia (Y.) enterocolitica</i>, an etiological agent of yersiniosis, is a bacterium whose pathogenicity is determined, among other things, by its ability to produce toxins. The aim of this article was to present the most important toxins that are produced by biotype 1A strains of <i>Y. enterocolitica</i>, and to discuss their role in the pathogenesis of yersiniosis. <i>Y. enterocolitica</i> biotype 1A strains are able to synthesize variants of thermostable YST enterotoxin and play a key role in the pathogenesis of yersiniosis. Biotype 1A strains of <i>Y. enterocolitica</i> also produce <i>Y. enterocolitica</i> pore-forming toxins, YaxA and YaxB. These toxins form pores in the cell membrane of host target cells and cause osmotic lysis, which is of particular importance in systemic infections. Insecticidal toxin complex genes have been detected in some clinical biotype 1A strains of <i>Y. enterocolitica</i>. However, their role has not yet been fully elucidated. Strains belonging to biotype 1A have long been considered non-pathogenic. This view is beginning to change due to the emerging knowledge about the toxigenic potential of these bacteria and their ability to overcome the defense barriers of the host organism. |
| first_indexed | 2024-03-09T20:55:32Z |
| format | Article |
| id | doaj.art-7a36cd1d374345d783dd4927b6059bf7 |
| institution | Directory Open Access Journal |
| issn | 2072-6651 |
| language | English |
| last_indexed | 2024-03-09T20:55:32Z |
| publishDate | 2022-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Toxins |
| spelling | doaj.art-7a36cd1d374345d783dd4927b6059bf72023-11-23T22:21:40ZengMDPI AGToxins2072-66512022-02-0114211810.3390/toxins14020118Toxigenic Properties of <i>Yersinia enterocolitica</i> Biotype 1AAleksandra Platt-Samoraj0Department of Epizootiology, Faculty of Veterinary Medicine, University of Warmia and Mazury, 10-718 Olsztyn, Poland<i>Yersinia (Y.) enterocolitica</i>, an etiological agent of yersiniosis, is a bacterium whose pathogenicity is determined, among other things, by its ability to produce toxins. The aim of this article was to present the most important toxins that are produced by biotype 1A strains of <i>Y. enterocolitica</i>, and to discuss their role in the pathogenesis of yersiniosis. <i>Y. enterocolitica</i> biotype 1A strains are able to synthesize variants of thermostable YST enterotoxin and play a key role in the pathogenesis of yersiniosis. Biotype 1A strains of <i>Y. enterocolitica</i> also produce <i>Y. enterocolitica</i> pore-forming toxins, YaxA and YaxB. These toxins form pores in the cell membrane of host target cells and cause osmotic lysis, which is of particular importance in systemic infections. Insecticidal toxin complex genes have been detected in some clinical biotype 1A strains of <i>Y. enterocolitica</i>. However, their role has not yet been fully elucidated. Strains belonging to biotype 1A have long been considered non-pathogenic. This view is beginning to change due to the emerging knowledge about the toxigenic potential of these bacteria and their ability to overcome the defense barriers of the host organism.https://www.mdpi.com/2072-6651/14/2/118<i>Yersinia enterocolitica</i>biotype 1AtoxinsYST-bYSY-cinsecticidal toxins |
| spellingShingle | Aleksandra Platt-Samoraj Toxigenic Properties of <i>Yersinia enterocolitica</i> Biotype 1A Toxins <i>Yersinia enterocolitica</i> biotype 1A toxins YST-b YSY-c insecticidal toxins |
| title | Toxigenic Properties of <i>Yersinia enterocolitica</i> Biotype 1A |
| title_full | Toxigenic Properties of <i>Yersinia enterocolitica</i> Biotype 1A |
| title_fullStr | Toxigenic Properties of <i>Yersinia enterocolitica</i> Biotype 1A |
| title_full_unstemmed | Toxigenic Properties of <i>Yersinia enterocolitica</i> Biotype 1A |
| title_short | Toxigenic Properties of <i>Yersinia enterocolitica</i> Biotype 1A |
| title_sort | toxigenic properties of i yersinia enterocolitica i biotype 1a |
| topic | <i>Yersinia enterocolitica</i> biotype 1A toxins YST-b YSY-c insecticidal toxins |
| url | https://www.mdpi.com/2072-6651/14/2/118 |
| work_keys_str_mv | AT aleksandraplattsamoraj toxigenicpropertiesofiyersiniaenterocoliticaibiotype1a |