Cytotoxicity towards Breast Cancer Cells of Pluronic F-127/Hyaluronic Acid Hydrogel Containing Nitric Oxide Donor and Silica Nanoparticles Loaded with Cisplatin

Cytotoxicity towards Breast Cancer Cells of Pluronic F-127/Hyaluronic Acid Hydrogel Containing Nitric Oxide Donor and Silica Nanoparticles Loaded with Cisplatin

The incorporation of both nitric oxide (NO) donor (S-nitrosoglutathione, GSNO) and silica nanoparticles loaded with cisplatin (SiO<sub>2</sub>@CisPt NPs) into a polymeric matrix represents a suitable approach to creating a drug-delivery system with sustained and localized drug release ag...

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Bibliographic Details
Main Authors: Bianca de Melo Santana, Joana Claudio Pieretti, Rafael Nunes Gomes, Giselle Cerchiaro, Amedea Barozzi Seabra
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Pharmaceutics
Subjects:
nitric oxide
nanoparticles
hydrogel
cytotoxicity
drug delivery
breast cancer cells
Online Access:https://www.mdpi.com/1999-4923/14/12/2837

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