Protective effects of prebiotic in zebrafish, Danio rerio, under experimental exposure to Chlorpyrifos
The current study estimated the immunotoxicological effects of the herbicide chlorpyrifos at sub-lethal concentration and the potential ameliorative effects of galactooligosaccharide (GOS) in Danio rerio. Fish was sampled after a 56-days feeding with GOS and then exposed to 15 mg/l chlorpyrifos for...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
University of Tehran
2018-04-01
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| Series: | International Journal of Aquatic Biology |
| Subjects: | |
| Online Access: | http://ij-aquaticbiology.com/index.php/ijab/article/view/364 |
| Summary: | The current study estimated the immunotoxicological effects of the herbicide chlorpyrifos at sub-lethal concentration and the potential ameliorative effects of galactooligosaccharide (GOS) in Danio rerio. Fish was sampled after a 56-days feeding with GOS and then exposed to 15 mg/l chlorpyrifos for 7-days to assess the non-specific immune responses (total protein, immunoglobulin and ALP activity). The results revealed that feeding zebrafish with 1% dietary GOS increased total protein levels (P<0.05), but no significant effect was noticed between groups fed 0.5 and 2% GOS and control (P>0.05). There were significant difference between total immunoglobulin levels 1% and control group (P<0.05). Furthermore, in case of ALP activity no significant alteration was noticed between GOS fed fish and control (P>0.05). The present findings revealed that dietary supplementation with GOS could be useful for modulation of the immunity in response to chlorpyrifos exposure, thereby presenting a promising feed additive in aquaculture. |
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| ISSN: | 2383-0956 2322-5270 |