Relationship between spectral domain optical coherence tomography and the perimetry automated in glaucoma suspect and glaucoma in hispanic population
Purpose: The aim of the study is to evaluate the structure-function relationship measured with NIDEK RS-3000 advance spectral-domain optical coherence tomography and standard automated perimetry (SAP) in a Hispanic population. Methods: Eighty-three eyes with open-angle glaucoma (mean age: 63.4 years...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2019-01-01
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| Series: | The Pan-American Journal of Ophthalmology |
| Subjects: | |
| Online Access: | http://www.thepajo.org/article.asp?issn=2666-4909;year=2019;volume=1;issue=1;spage=2;epage=2;aulast=Toquica |
| _version_ | 1818891106857779200 |
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| author | Jeanneth Toquica Fernando Gomez-Goyeneche Maryudi Velandia-Plata Diana Sarmiento-Forero Gerardo Ardila-Duarte |
| author_facet | Jeanneth Toquica Fernando Gomez-Goyeneche Maryudi Velandia-Plata Diana Sarmiento-Forero Gerardo Ardila-Duarte |
| author_sort | Jeanneth Toquica |
| collection | DOAJ |
| description | Purpose: The aim of the study is to evaluate the structure-function relationship measured with NIDEK RS-3000 advance spectral-domain optical coherence tomography and standard automated perimetry (SAP) in a Hispanic population.
Methods: Eighty-three eyes with open-angle glaucoma (mean age: 63.4 years, 24% male and 76% female) and 163 eyes with glaucoma suspects (mean age: 51.6 years, 38% male and 62% female) were included in a cross-sectional study. The connection between retinal nerve fiber layer (RNFL), optic disc and ganglion cell complex (GCC) reduction, and visual field losses were evaluated, and Pearson's correlation coefficients (R) was calculated.
Results: A significant but mild correlation (R = 0.24; P < 0.002) was seen between functional and structural parameters in glaucoma suspects. After the classification of the patients by the Hodapp–Parrish–Anderson glaucoma grading scale, at mild glaucoma, it was established a significant correlation between SAP with temporal RNFL (R = 0314; P < 0.003) and optic disc (R = 0.36; P < 0.012). In relation to moderate glaucoma, it was found a higher correlation between temporal thinning of RNFL (R = 0.734; P < 0.005) and inferior GCC (R = 0.506; P < 0.023). At advanced glaucoma, there was a stronger correlation (R = 0.711;xz P < 0.014) between superior RNFL and optic disc with corresponding topographic SAP locations.
Conclusions: There were significant correlations between RNFL, optic disc and GCC loss, and deficits on SAP that increase with the glaucoma severity. This damage could be predictive of visual field loss, the defects went from generalized to localized, and the change rates were directly related to the stage of the disease. |
| first_indexed | 2024-12-19T17:35:32Z |
| format | Article |
| id | doaj.art-7a3f87b941ce47ad8ba5d53b43801330 |
| institution | Directory Open Access Journal |
| issn | 2666-4909 2666-4909 |
| language | English |
| last_indexed | 2024-12-19T17:35:32Z |
| publishDate | 2019-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | The Pan-American Journal of Ophthalmology |
| spelling | doaj.art-7a3f87b941ce47ad8ba5d53b438013302022-12-21T20:12:21ZengWolters Kluwer Medknow PublicationsThe Pan-American Journal of Ophthalmology2666-49092666-49092019-01-01112210.4103/PAJO.PAJO_10_19Relationship between spectral domain optical coherence tomography and the perimetry automated in glaucoma suspect and glaucoma in hispanic populationJeanneth ToquicaFernando Gomez-GoyenecheMaryudi Velandia-PlataDiana Sarmiento-ForeroGerardo Ardila-DuartePurpose: The aim of the study is to evaluate the structure-function relationship measured with NIDEK RS-3000 advance spectral-domain optical coherence tomography and standard automated perimetry (SAP) in a Hispanic population. Methods: Eighty-three eyes with open-angle glaucoma (mean age: 63.4 years, 24% male and 76% female) and 163 eyes with glaucoma suspects (mean age: 51.6 years, 38% male and 62% female) were included in a cross-sectional study. The connection between retinal nerve fiber layer (RNFL), optic disc and ganglion cell complex (GCC) reduction, and visual field losses were evaluated, and Pearson's correlation coefficients (R) was calculated. Results: A significant but mild correlation (R = 0.24; P < 0.002) was seen between functional and structural parameters in glaucoma suspects. After the classification of the patients by the Hodapp–Parrish–Anderson glaucoma grading scale, at mild glaucoma, it was established a significant correlation between SAP with temporal RNFL (R = 0314; P < 0.003) and optic disc (R = 0.36; P < 0.012). In relation to moderate glaucoma, it was found a higher correlation between temporal thinning of RNFL (R = 0.734; P < 0.005) and inferior GCC (R = 0.506; P < 0.023). At advanced glaucoma, there was a stronger correlation (R = 0.711;xz P < 0.014) between superior RNFL and optic disc with corresponding topographic SAP locations. Conclusions: There were significant correlations between RNFL, optic disc and GCC loss, and deficits on SAP that increase with the glaucoma severity. This damage could be predictive of visual field loss, the defects went from generalized to localized, and the change rates were directly related to the stage of the disease.http://www.thepajo.org/article.asp?issn=2666-4909;year=2019;volume=1;issue=1;spage=2;epage=2;aulast=Toquicaganglion cell complexoptical coherence tomographyretinal nerve fiber layervisual field |
| spellingShingle | Jeanneth Toquica Fernando Gomez-Goyeneche Maryudi Velandia-Plata Diana Sarmiento-Forero Gerardo Ardila-Duarte Relationship between spectral domain optical coherence tomography and the perimetry automated in glaucoma suspect and glaucoma in hispanic population The Pan-American Journal of Ophthalmology ganglion cell complex optical coherence tomography retinal nerve fiber layer visual field |
| title | Relationship between spectral domain optical coherence tomography and the perimetry automated in glaucoma suspect and glaucoma in hispanic population |
| title_full | Relationship between spectral domain optical coherence tomography and the perimetry automated in glaucoma suspect and glaucoma in hispanic population |
| title_fullStr | Relationship between spectral domain optical coherence tomography and the perimetry automated in glaucoma suspect and glaucoma in hispanic population |
| title_full_unstemmed | Relationship between spectral domain optical coherence tomography and the perimetry automated in glaucoma suspect and glaucoma in hispanic population |
| title_short | Relationship between spectral domain optical coherence tomography and the perimetry automated in glaucoma suspect and glaucoma in hispanic population |
| title_sort | relationship between spectral domain optical coherence tomography and the perimetry automated in glaucoma suspect and glaucoma in hispanic population |
| topic | ganglion cell complex optical coherence tomography retinal nerve fiber layer visual field |
| url | http://www.thepajo.org/article.asp?issn=2666-4909;year=2019;volume=1;issue=1;spage=2;epage=2;aulast=Toquica |
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