Hydroxysafflor Yellow A Suppresses MRC-5 Cell Activation Induced by TGF-β1 by Blocking TGF-β1 Binding to TβRII

Hydroxysafflor Yellow A Suppresses MRC-5 Cell Activation Induced by TGF-β1 by Blocking TGF-β1 Binding to TβRII

Hydroxysafflor yellow A (HSYA) is an active ingredient of Carthamus tinctorius L.. This study aimed to evaluate the effects of HSYA on transforming growth factor-β1 (TGF-β1)-induced changes in proliferation, migration, differentiation, and extracellular matrix accumulation and degradation in human f...

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Bibliographic Details
Main Authors: Ruiyan Pan, Yadan Zhang, Meng Zheng, Baoxia Zang, Ming Jin
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-05-01
Series:Frontiers in Pharmacology
Subjects:
hydroxysafflor yellow A
TGF-β1
TβRII
Smad
fibroblast
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2017.00264/full

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