MTRR rs326119 polymorphism is associated with plasma concentrations of homocysteine and cobalamin, but not with congenital heart disease or coronary atherosclerosis in Brazilian patients

MTRR rs326119 polymorphism is associated with plasma concentrations of homocysteine and cobalamin, but not with congenital heart disease or coronary atherosclerosis in Brazilian patients

Background: Differences in the distribution of the MTRR rs326119 polymorphism (c.56+781 A>C) between patients with congenital heart disease (CHD) and controls have been described in Chinese individuals. The association is thought to be due to deregulation of homocysteine-cobalamin pathways. This...

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Bibliographic Details
Main Authors: Melanie Horita, Carolina Tosin Bueno, Andrea R Horimoto, Pedro A Lemos, Antonio A Morandini-Filho, Jose E Krieger, Paulo C J L Santos, Alexandre C Pereira
Format: Article
Language:English
Published: Elsevier 2017-03-01
Series:International Journal of Cardiology: Heart & Vasculature
Subjects:
MTRR gene
rs326119
Congenital heart disease
Homocysteine
Cobalamin
Online Access:http://www.sciencedirect.com/science/article/pii/S2352906716300884

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http://www.sciencedirect.com/science/article/pii/S2352906716300884

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