Prevalence of Congenital Toxoplasmosis and Congenital Rubella among Suspected Infants in Baghdad
Congenital toxoplasmosis (CT) and congenital rubella (CR) infections are well-known causes potentially leading to devastating consequences. This report aims to address the prevalence of each of these infections among suspected infants in a pediatric hospital in Baghdad. The study sample includes...
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| Format: | Article |
| Language: | English |
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University of Baghdad/ Al-Kindy College of Medicine
2022-12-01
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| Series: | مجله كليه طب الكندي |
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| Online Access: | https://jkmc.uobaghdad.edu.iq/index.php/MEDICAL/article/view/854 |
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| author | Tareef Fadhil Raham Ahmed Nabeel Abdul-Wahab Zainab Ali Chaloub |
| author_facet | Tareef Fadhil Raham Ahmed Nabeel Abdul-Wahab Zainab Ali Chaloub |
| author_sort | Tareef Fadhil Raham |
| collection | DOAJ |
| description |
Congenital toxoplasmosis (CT) and congenital rubella (CR) infections are well-known causes potentially leading to devastating consequences. This report aims to address the prevalence of each of these infections among suspected infants in a pediatric hospital in Baghdad.
The study sample includes 120 blood samples of suspected infants consulting Al-Alwyia pediatric teaching hospital over one year. This report represents an extension of a previous article published in Al-Kindy College Medical Journal KCMJ about cytomegalovirus infection (CMV). Using the enzyme-linked immunosorbent assay (ELISA) method, the results show that 5.8% and 5% were positive for specific IgM antibodies for rubella and toxoplasmosis respectively. Results also show that CMV is more common than CT and CR.
Although results reported one case of co-existence of IgM antibodies for both CMV and rubella, there was a significant association of negative CMV IgG and IgM results with positive rubella results; and negative rubella results with CMV IgG and IgM results.
Conclusions: This short brief addressed the prevalence of CT and CR in Baghdad. A novel finding identified in this brief is the association of the prevalence of CR active infection with negative past and negative recent CMV infections, and the association of prevalence of CMV active and past infections with negative CR infection
Recommendations: The study recommends increased awareness, early diagnosis and treatment for congenital infection, and consolidation of coverage of the rubella vaccine for children and girls at premarital age.
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| first_indexed | 2024-04-11T04:14:06Z |
| format | Article |
| id | doaj.art-7a454cb1ae474625a69da41d463f022d |
| institution | Directory Open Access Journal |
| issn | 1810-9543 2521-4365 |
| language | English |
| last_indexed | 2024-04-11T04:14:06Z |
| publishDate | 2022-12-01 |
| publisher | University of Baghdad/ Al-Kindy College of Medicine |
| record_format | Article |
| series | مجله كليه طب الكندي |
| spelling | doaj.art-7a454cb1ae474625a69da41d463f022d2022-12-31T23:37:40ZengUniversity of Baghdad/ Al-Kindy College of Medicineمجله كليه طب الكندي1810-95432521-43652022-12-0118310.47723/kcmj.v18i3.854Prevalence of Congenital Toxoplasmosis and Congenital Rubella among Suspected Infants in BaghdadTareef Fadhil Raham0Ahmed Nabeel Abdul-WahabZainab Ali Chaloub Al- Alwia pediatric teaching H. MOH - IRAQ Congenital toxoplasmosis (CT) and congenital rubella (CR) infections are well-known causes potentially leading to devastating consequences. This report aims to address the prevalence of each of these infections among suspected infants in a pediatric hospital in Baghdad. The study sample includes 120 blood samples of suspected infants consulting Al-Alwyia pediatric teaching hospital over one year. This report represents an extension of a previous article published in Al-Kindy College Medical Journal KCMJ about cytomegalovirus infection (CMV). Using the enzyme-linked immunosorbent assay (ELISA) method, the results show that 5.8% and 5% were positive for specific IgM antibodies for rubella and toxoplasmosis respectively. Results also show that CMV is more common than CT and CR. Although results reported one case of co-existence of IgM antibodies for both CMV and rubella, there was a significant association of negative CMV IgG and IgM results with positive rubella results; and negative rubella results with CMV IgG and IgM results. Conclusions: This short brief addressed the prevalence of CT and CR in Baghdad. A novel finding identified in this brief is the association of the prevalence of CR active infection with negative past and negative recent CMV infections, and the association of prevalence of CMV active and past infections with negative CR infection Recommendations: The study recommends increased awareness, early diagnosis and treatment for congenital infection, and consolidation of coverage of the rubella vaccine for children and girls at premarital age. https://jkmc.uobaghdad.edu.iq/index.php/MEDICAL/article/view/854Congenital ToxoplasmosisCongenital RubellaIgM antibodies |
| spellingShingle | Tareef Fadhil Raham Ahmed Nabeel Abdul-Wahab Zainab Ali Chaloub Prevalence of Congenital Toxoplasmosis and Congenital Rubella among Suspected Infants in Baghdad مجله كليه طب الكندي Congenital Toxoplasmosis Congenital Rubella IgM antibodies |
| title | Prevalence of Congenital Toxoplasmosis and Congenital Rubella among Suspected Infants in Baghdad |
| title_full | Prevalence of Congenital Toxoplasmosis and Congenital Rubella among Suspected Infants in Baghdad |
| title_fullStr | Prevalence of Congenital Toxoplasmosis and Congenital Rubella among Suspected Infants in Baghdad |
| title_full_unstemmed | Prevalence of Congenital Toxoplasmosis and Congenital Rubella among Suspected Infants in Baghdad |
| title_short | Prevalence of Congenital Toxoplasmosis and Congenital Rubella among Suspected Infants in Baghdad |
| title_sort | prevalence of congenital toxoplasmosis and congenital rubella among suspected infants in baghdad |
| topic | Congenital Toxoplasmosis Congenital Rubella IgM antibodies |
| url | https://jkmc.uobaghdad.edu.iq/index.php/MEDICAL/article/view/854 |
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