Obesity and related comorbidities in a large population-based cohort of subjects with type 1 diabetes in Catalonia
IntroductionObesity, an increasing global health problem, can affect people with other disease conditions. The prevalence of obesity in people with type 1 diabetes (T1D) is not well known. The aim of this study was to describe extensively the characteristics and prevalence of different classes of ob...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-12-01
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| Series: | Frontiers in Endocrinology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fendo.2022.1015614/full |
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| author | Idoia Genua Idoia Genua Idoia Genua Josep Franch-Nadal Josep Franch-Nadal Josep Franch-Nadal Elena Navas Manel Mata-Cases Manel Mata-Cases Manel Mata-Cases Gabriel Giménez-Pérez Gabriel Giménez-Pérez Bogdan Vlacho Bogdan Vlacho Bogdan Vlacho Didac Mauricio Didac Mauricio Didac Mauricio Didac Mauricio Albert Goday Albert Goday Albert Goday |
| author_facet | Idoia Genua Idoia Genua Idoia Genua Josep Franch-Nadal Josep Franch-Nadal Josep Franch-Nadal Elena Navas Manel Mata-Cases Manel Mata-Cases Manel Mata-Cases Gabriel Giménez-Pérez Gabriel Giménez-Pérez Bogdan Vlacho Bogdan Vlacho Bogdan Vlacho Didac Mauricio Didac Mauricio Didac Mauricio Didac Mauricio Albert Goday Albert Goday Albert Goday |
| author_sort | Idoia Genua |
| collection | DOAJ |
| description | IntroductionObesity, an increasing global health problem, can affect people with other disease conditions. The prevalence of obesity in people with type 1 diabetes (T1D) is not well known. The aim of this study was to describe extensively the characteristics and prevalence of different classes of obesity according to BMI (body mass index) categories in a large cohort of patients with T1D.Material and methodsThis was a retrospective, cross-sectional study in Catalonia. We reviewed all patients with T1D diagnosis, ≥ 18 years old and with BMI data from the SIDIAP database. Sociodemographic and clinical data, cardiovascular risk factors, laboratory parameters and concomitant medications were collected.ResultsA total of 6,068 patients with T1D were analyzed. The prevalence of obesity in the total sample was 18% (13.8% with class 1 obesity [BMI 30-34.9 kg/m2]). Patients with obesity had a higher prevalence of other cardiovascular risk factors (i.e. hypertension was 61.4% vs. 37.5%; dyslipidemia 63.6% vs 44%, and chronic kidney disease 38.4% vs. 24.4%; p<0.001 in all cases) and poorer control of them. The higher prevalence was regardless of sex, age and duration of diabetes. The increase in these comorbidities was noticeable from a BMI > 25 kg/m2. Patients with obesity did not have poorer glycemic control.ConclusionThe presence of obesity in people with T1D is frequent and cardiovascular risk factors are more common and more poorly controlled in T1D patients with obesity. |
| first_indexed | 2024-04-11T15:49:11Z |
| format | Article |
| id | doaj.art-7a4b04a9ead84f188954bf83d7c62c6e |
| institution | Directory Open Access Journal |
| issn | 1664-2392 |
| language | English |
| last_indexed | 2024-04-11T15:49:11Z |
| publishDate | 2022-12-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Endocrinology |
| spelling | doaj.art-7a4b04a9ead84f188954bf83d7c62c6e2022-12-22T04:15:23ZengFrontiers Media S.A.Frontiers in Endocrinology1664-23922022-12-011310.3389/fendo.2022.10156141015614Obesity and related comorbidities in a large population-based cohort of subjects with type 1 diabetes in CataloniaIdoia Genua0Idoia Genua1Idoia Genua2Josep Franch-Nadal3Josep Franch-Nadal4Josep Franch-Nadal5Elena Navas6Manel Mata-Cases7Manel Mata-Cases8Manel Mata-Cases9Gabriel Giménez-Pérez10Gabriel Giménez-Pérez11Bogdan Vlacho12Bogdan Vlacho13Bogdan Vlacho14Didac Mauricio15Didac Mauricio16Didac Mauricio17Didac Mauricio18Albert Goday19Albert Goday20Albert Goday21Department of Endocrinology and Nutrition, Hospital de la Santa Creu i Sant Pau, Barcelona, SpainDepartment of Medicine, Autonomous University of Barcelona, Barcelona, SpainInstitut d’Investigació Biomèdica Sant Pau (IIB SANT PAU), Barcelona, SpainDiabetis en Atenció Primaria-Catalunya (DAP-Cat) group, Unitat de Suport a la Recerca Barcelona, Fundació Institut Universitari per a la recerca a l’Atenció Primària de Salut Jordi Gol i Gurina (IDIAPJGol), Barcelona, SpainPrimary Health Care Center Raval Sud, Gerència d’Atenció Primaria, Institut Català de la Salut, Barcelona, SpainCentro de Investigación Biomédica en Red (CIBER) of Diabetes and Associated Metabolic Diseases (CIBERDEM), Instituto de Salud Carlos III (ISCIII), Barcelona, SpainUnitat de Suport a la Recerca|, Barcelona, SpainDiabetis en Atenció Primaria-Catalunya (DAP-Cat) group, Unitat de Suport a la Recerca Barcelona, Fundació Institut Universitari per a la recerca a l’Atenció Primària de Salut Jordi Gol i Gurina (IDIAPJGol), Barcelona, SpainCentro de Investigación Biomédica en Red (CIBER) of Diabetes and Associated Metabolic Diseases (CIBERDEM), Instituto de Salud Carlos III (ISCIII), Barcelona, SpainPrimary Health Care Center La Mina, Gerència d’Atenció Primària Barcelona Ciutat, Institut Català de la Salut, Sant Adrià de Besòs, SpainEndocrinology Section, Department of Medicine, Hospital General de Granollers, Granollers, Spain0School of Medicine and Health Sciences, Universitat Internacional de Catalunya, Sant Cugat del Vallès, SpainInstitut d’Investigació Biomèdica Sant Pau (IIB SANT PAU), Barcelona, SpainDiabetis en Atenció Primaria-Catalunya (DAP-Cat) group, Unitat de Suport a la Recerca Barcelona, Fundació Institut Universitari per a la recerca a l’Atenció Primària de Salut Jordi Gol i Gurina (IDIAPJGol), Barcelona, SpainCentro de Investigación Biomédica en Red (CIBER) of Diabetes and Associated Metabolic Diseases (CIBERDEM), Instituto de Salud Carlos III (ISCIII), Barcelona, SpainDepartment of Endocrinology and Nutrition, Hospital de la Santa Creu i Sant Pau, Barcelona, SpainDiabetis en Atenció Primaria-Catalunya (DAP-Cat) group, Unitat de Suport a la Recerca Barcelona, Fundació Institut Universitari per a la recerca a l’Atenció Primària de Salut Jordi Gol i Gurina (IDIAPJGol), Barcelona, SpainCentro de Investigación Biomédica en Red (CIBER) of Diabetes and Associated Metabolic Diseases (CIBERDEM), Instituto de Salud Carlos III (ISCIII), Barcelona, Spain1Department of Medicine, Universitat de Vic - Universitat Central de Catalunya, Barcelona, SpainDepartment of Medicine, Autonomous University of Barcelona, Barcelona, Spain2Deparment of Endocrinology & Nutrition, Hospital del Mar, IMIM Institut Mar d’Investigacions Mediques. Parc de Salut Mar, Barcelona, Spain3CIBERobn, Instituto de Salud Carlos III (ISCIII), Madrid, SpainIntroductionObesity, an increasing global health problem, can affect people with other disease conditions. The prevalence of obesity in people with type 1 diabetes (T1D) is not well known. The aim of this study was to describe extensively the characteristics and prevalence of different classes of obesity according to BMI (body mass index) categories in a large cohort of patients with T1D.Material and methodsThis was a retrospective, cross-sectional study in Catalonia. We reviewed all patients with T1D diagnosis, ≥ 18 years old and with BMI data from the SIDIAP database. Sociodemographic and clinical data, cardiovascular risk factors, laboratory parameters and concomitant medications were collected.ResultsA total of 6,068 patients with T1D were analyzed. The prevalence of obesity in the total sample was 18% (13.8% with class 1 obesity [BMI 30-34.9 kg/m2]). Patients with obesity had a higher prevalence of other cardiovascular risk factors (i.e. hypertension was 61.4% vs. 37.5%; dyslipidemia 63.6% vs 44%, and chronic kidney disease 38.4% vs. 24.4%; p<0.001 in all cases) and poorer control of them. The higher prevalence was regardless of sex, age and duration of diabetes. The increase in these comorbidities was noticeable from a BMI > 25 kg/m2. Patients with obesity did not have poorer glycemic control.ConclusionThe presence of obesity in people with T1D is frequent and cardiovascular risk factors are more common and more poorly controlled in T1D patients with obesity.https://www.frontiersin.org/articles/10.3389/fendo.2022.1015614/fullObesitytype 1 diabetescardiovascular risk factorsmetabolic syndromecomorbidities |
| spellingShingle | Idoia Genua Idoia Genua Idoia Genua Josep Franch-Nadal Josep Franch-Nadal Josep Franch-Nadal Elena Navas Manel Mata-Cases Manel Mata-Cases Manel Mata-Cases Gabriel Giménez-Pérez Gabriel Giménez-Pérez Bogdan Vlacho Bogdan Vlacho Bogdan Vlacho Didac Mauricio Didac Mauricio Didac Mauricio Didac Mauricio Albert Goday Albert Goday Albert Goday Obesity and related comorbidities in a large population-based cohort of subjects with type 1 diabetes in Catalonia Frontiers in Endocrinology Obesity type 1 diabetes cardiovascular risk factors metabolic syndrome comorbidities |
| title | Obesity and related comorbidities in a large population-based cohort of subjects with type 1 diabetes in Catalonia |
| title_full | Obesity and related comorbidities in a large population-based cohort of subjects with type 1 diabetes in Catalonia |
| title_fullStr | Obesity and related comorbidities in a large population-based cohort of subjects with type 1 diabetes in Catalonia |
| title_full_unstemmed | Obesity and related comorbidities in a large population-based cohort of subjects with type 1 diabetes in Catalonia |
| title_short | Obesity and related comorbidities in a large population-based cohort of subjects with type 1 diabetes in Catalonia |
| title_sort | obesity and related comorbidities in a large population based cohort of subjects with type 1 diabetes in catalonia |
| topic | Obesity type 1 diabetes cardiovascular risk factors metabolic syndrome comorbidities |
| url | https://www.frontiersin.org/articles/10.3389/fendo.2022.1015614/full |
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