Monocytes acquire prostate cancer specific chromatin conformations upon indirect co-culture with prostate cancer cells

Monocytes acquire prostate cancer specific chromatin conformations upon indirect co-culture with prostate cancer cells

BackgroundThree-dimensional chromosome loop conformations are powerful regulators of gene expression. These chromosome conformations can be detected both in tumour and in circulating cells and have significant disease biomarker potential. We have recently detected specific chromosome conformations i...

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Bibliographic Details
Main Authors: Heba Alshaker, Ewan Hunter, Matthew Salter, Aroul Ramadass, Willem Westra, Mathias Winkler, Jayne Green, Alexandre Akoulitchev, Dmitri Pchejetski
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Oncology
Subjects:
prostate cancer
nucleome
3C
blood test
horizontal gene transfer
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.990842/full

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