Analysis of the common complications and recurrence-related factors of superior parasagittal sinus meningioma
ObjectivesParasagittal meningioma resection is prone to postoperative complications and tumor recurrence because the tumor invades the superior sagittal sinus. This study aimed to clarify the incidence of perioperative complications and the recurrence of superior sagittal paranasal meningiomas and e...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-01-01
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| Series: | Frontiers in Surgery |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fsurg.2022.1023021/full |
| _version_ | 1797960119808425984 |
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| author | Wei-Wei Chen Wei-Wei Chen Yong Wang Yang-Chun Hu Yuan-Li Zhao |
| author_facet | Wei-Wei Chen Wei-Wei Chen Yong Wang Yang-Chun Hu Yuan-Li Zhao |
| author_sort | Wei-Wei Chen |
| collection | DOAJ |
| description | ObjectivesParasagittal meningioma resection is prone to postoperative complications and tumor recurrence because the tumor invades the superior sagittal sinus. This study aimed to clarify the incidence of perioperative complications and the recurrence of superior sagittal paranasal meningiomas and explored potential predictors in this context.MethodsThe study retrospectively reviewed the clinical, imaging, and follow-up data of parasagittal meningiomas among patients who underwent microsurgical resection in the authors' institution from January 2008 to December 2017. Univariate and multivariate logistic regression analyses were conducted to explore independent predictors of perioperative complications and tumor recurrence.ResultsA total of 212 parasagittal meningioma patients were included in this study. The incidence of perioperative complications was 23.6% (50/212), and perioperative death occurred in 6 (2.8%) patients. In univariate and multivariate logistic regression analyses of perioperative complications, peritumoral edema ≥1 cm (odds ratio [OR] 2.163, 95% confidence interval [CI] 1.057–4.428, P = 0.035) and the Sindou invasion Class V-VI(OR0.018, 95% CI 1.248–11.064, P = 0.018) were independent predictors. After an average of 83 (39–154) months of clinical follow up among the living 206 patients, 22 (10.7%) patients showed tumor recurrence. In univariate and multivariate logistic regression analyses of tumor recurrence, the Sindou invasion Class III-IV (OR 5.539, 95%CI 1.469–20.884, P = 0.011) and the Sindou invasion Class V-VI (OR 9.144, 95%CI 2.215–37.757, P = 0.002) were independent predictors.ConclusionsPeritumoral edema ≥1 cm and the Sindou invasion Class V-VI were the independent predictors of perioperative complications, and the Sindou invasion Class III-IV and the Sindou invasion Class V-VI were the independent predictors of tumor recurrence. The part of the parasagittal meningioma involving the sinus wall should be actively removed to the largest degree possible to reduce the recurrence rate. |
| first_indexed | 2024-04-11T00:40:24Z |
| format | Article |
| id | doaj.art-7a4cba51a2b24f6182a6c4f80eab2405 |
| institution | Directory Open Access Journal |
| issn | 2296-875X |
| language | English |
| last_indexed | 2024-04-11T00:40:24Z |
| publishDate | 2023-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Surgery |
| spelling | doaj.art-7a4cba51a2b24f6182a6c4f80eab24052023-01-06T05:47:41ZengFrontiers Media S.A.Frontiers in Surgery2296-875X2023-01-01910.3389/fsurg.2022.10230211023021Analysis of the common complications and recurrence-related factors of superior parasagittal sinus meningiomaWei-Wei Chen0Wei-Wei Chen1Yong Wang2Yang-Chun Hu3Yuan-Li Zhao4Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, ChinaDepartment of Neurosurgery, The First Affiliated Hospital of Anhui Medical University, Hefei, ChinaDepartment of Neurosurgery, The First Affiliated Hospital of Anhui Medical University, Hefei, ChinaDepartment of Neurosurgery, The First Affiliated Hospital of Anhui Medical University, Hefei, ChinaDepartment of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, ChinaObjectivesParasagittal meningioma resection is prone to postoperative complications and tumor recurrence because the tumor invades the superior sagittal sinus. This study aimed to clarify the incidence of perioperative complications and the recurrence of superior sagittal paranasal meningiomas and explored potential predictors in this context.MethodsThe study retrospectively reviewed the clinical, imaging, and follow-up data of parasagittal meningiomas among patients who underwent microsurgical resection in the authors' institution from January 2008 to December 2017. Univariate and multivariate logistic regression analyses were conducted to explore independent predictors of perioperative complications and tumor recurrence.ResultsA total of 212 parasagittal meningioma patients were included in this study. The incidence of perioperative complications was 23.6% (50/212), and perioperative death occurred in 6 (2.8%) patients. In univariate and multivariate logistic regression analyses of perioperative complications, peritumoral edema ≥1 cm (odds ratio [OR] 2.163, 95% confidence interval [CI] 1.057–4.428, P = 0.035) and the Sindou invasion Class V-VI(OR0.018, 95% CI 1.248–11.064, P = 0.018) were independent predictors. After an average of 83 (39–154) months of clinical follow up among the living 206 patients, 22 (10.7%) patients showed tumor recurrence. In univariate and multivariate logistic regression analyses of tumor recurrence, the Sindou invasion Class III-IV (OR 5.539, 95%CI 1.469–20.884, P = 0.011) and the Sindou invasion Class V-VI (OR 9.144, 95%CI 2.215–37.757, P = 0.002) were independent predictors.ConclusionsPeritumoral edema ≥1 cm and the Sindou invasion Class V-VI were the independent predictors of perioperative complications, and the Sindou invasion Class III-IV and the Sindou invasion Class V-VI were the independent predictors of tumor recurrence. The part of the parasagittal meningioma involving the sinus wall should be actively removed to the largest degree possible to reduce the recurrence rate.https://www.frontiersin.org/articles/10.3389/fsurg.2022.1023021/fullmeningiomacomplicationrecurrencesuperior parasagittal sinusneurosurgery |
| spellingShingle | Wei-Wei Chen Wei-Wei Chen Yong Wang Yang-Chun Hu Yuan-Li Zhao Analysis of the common complications and recurrence-related factors of superior parasagittal sinus meningioma Frontiers in Surgery meningioma complication recurrence superior parasagittal sinus neurosurgery |
| title | Analysis of the common complications and recurrence-related factors of superior parasagittal sinus meningioma |
| title_full | Analysis of the common complications and recurrence-related factors of superior parasagittal sinus meningioma |
| title_fullStr | Analysis of the common complications and recurrence-related factors of superior parasagittal sinus meningioma |
| title_full_unstemmed | Analysis of the common complications and recurrence-related factors of superior parasagittal sinus meningioma |
| title_short | Analysis of the common complications and recurrence-related factors of superior parasagittal sinus meningioma |
| title_sort | analysis of the common complications and recurrence related factors of superior parasagittal sinus meningioma |
| topic | meningioma complication recurrence superior parasagittal sinus neurosurgery |
| url | https://www.frontiersin.org/articles/10.3389/fsurg.2022.1023021/full |
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