Recent Advances in the Development of Biomimetic Materials
In this review, we focused on recent efforts in the design and development of materials with biomimetic properties. Innovative methods promise to emulate cell microenvironments and tissue functions, but many aspects regarding cellular communication, motility, and responsiveness remain to be explaine...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-10-01
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| Series: | Gels |
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| Online Access: | https://www.mdpi.com/2310-2861/9/10/833 |
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| author | Maria G. Ciulla Alessio Massironi Michela Sugni Matthew A. Ensign Stefania Marzorati Mahdi Forouharshad |
| author_facet | Maria G. Ciulla Alessio Massironi Michela Sugni Matthew A. Ensign Stefania Marzorati Mahdi Forouharshad |
| author_sort | Maria G. Ciulla |
| collection | DOAJ |
| description | In this review, we focused on recent efforts in the design and development of materials with biomimetic properties. Innovative methods promise to emulate cell microenvironments and tissue functions, but many aspects regarding cellular communication, motility, and responsiveness remain to be explained. We photographed the state-of-the-art advancements in biomimetics, and discussed the complexity of a “bottom-up” artificial construction of living systems, with particular highlights on hydrogels, collagen-based composites, surface modifications, and three-dimensional (3D) bioprinting applications. Fast-paced 3D printing and artificial intelligence, nevertheless, collide with reality: How difficult can it be to build reproducible biomimetic materials at a real scale in line with the complexity of living systems? Nowadays, science is in urgent need of bioengineering technologies for the practical use of bioinspired and biomimetics for medicine and clinics. |
| first_indexed | 2024-03-10T21:13:49Z |
| format | Article |
| id | doaj.art-7a50e463d6f84eddb569193074f66545 |
| institution | Directory Open Access Journal |
| issn | 2310-2861 |
| language | English |
| last_indexed | 2024-03-10T21:13:49Z |
| publishDate | 2023-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Gels |
| spelling | doaj.art-7a50e463d6f84eddb569193074f665452023-11-19T16:36:02ZengMDPI AGGels2310-28612023-10-0191083310.3390/gels9100833Recent Advances in the Development of Biomimetic MaterialsMaria G. Ciulla0Alessio Massironi1Michela Sugni2Matthew A. Ensign3Stefania Marzorati4Mahdi Forouharshad5Department of Chemistry, Università degli Studi di Milano, Via C. Golgi 19, 20133 Milan, ItalyDepartment of Environmental Science and Policy, Università degli Studi di Milano, Via Celoria 2, 20133 Milan, ItalyDepartment of Environmental Science and Policy, Università degli Studi di Milano, Via Celoria 2, 20133 Milan, ItalyFischell Department of Bioengineering, University of Maryland, College Park, MD 20742, USADepartment of Environmental Science and Policy, Università degli Studi di Milano, Via Celoria 2, 20133 Milan, ItalyDepartment of Ophthalmology, Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USAIn this review, we focused on recent efforts in the design and development of materials with biomimetic properties. Innovative methods promise to emulate cell microenvironments and tissue functions, but many aspects regarding cellular communication, motility, and responsiveness remain to be explained. We photographed the state-of-the-art advancements in biomimetics, and discussed the complexity of a “bottom-up” artificial construction of living systems, with particular highlights on hydrogels, collagen-based composites, surface modifications, and three-dimensional (3D) bioprinting applications. Fast-paced 3D printing and artificial intelligence, nevertheless, collide with reality: How difficult can it be to build reproducible biomimetic materials at a real scale in line with the complexity of living systems? Nowadays, science is in urgent need of bioengineering technologies for the practical use of bioinspired and biomimetics for medicine and clinics.https://www.mdpi.com/2310-2861/9/10/833biomimeticsbiocompatibilitytissue engineeringmechanical propertiesbiomimetic hydrogelscollagen |
| spellingShingle | Maria G. Ciulla Alessio Massironi Michela Sugni Matthew A. Ensign Stefania Marzorati Mahdi Forouharshad Recent Advances in the Development of Biomimetic Materials Gels biomimetics biocompatibility tissue engineering mechanical properties biomimetic hydrogels collagen |
| title | Recent Advances in the Development of Biomimetic Materials |
| title_full | Recent Advances in the Development of Biomimetic Materials |
| title_fullStr | Recent Advances in the Development of Biomimetic Materials |
| title_full_unstemmed | Recent Advances in the Development of Biomimetic Materials |
| title_short | Recent Advances in the Development of Biomimetic Materials |
| title_sort | recent advances in the development of biomimetic materials |
| topic | biomimetics biocompatibility tissue engineering mechanical properties biomimetic hydrogels collagen |
| url | https://www.mdpi.com/2310-2861/9/10/833 |
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