Efficiently targeted therapy of glioblastoma xenograft via multifunctional biomimetic nanodrugs

Efficiently targeted therapy of glioblastoma xenograft via multifunctional biomimetic nanodrugs

Abstract Background Glioblastoma multiforme (GBM) is a fatal malignant primary brain tumor in adults. The therapeutic efficacy of chemotherapeutic drugs is limited due to the blood-brain barrier (BBB), poor drug targeting, and short biological half-lives. Multifunctional biomimetic nanodrugs have gr...

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Bibliographic Details
Main Authors: Zhipeng Yao, Xiaochun Jiang, Hong Yao, Yafeng Wu, Fan Zhang, Cheng Wang, Chenxue Qi, Chenhui Zhao, Zeyu Wu, Min Qi, Jia Zhang, Xiaoxiang Cao, Zhichun Wang, Fei Wu, Chengyun Yao, Songqin Liu, Shizhang Ling, Hongping Xia
Format: Article
Language:English
Published: American Association for the Advancement of Science (AAAS) 2022-12-01
Series:Biomaterials Research
Subjects:
Glioblastoma
Doxorubicin
Biomimetic
Nanodrug
Antitumor
Online Access:https://doi.org/10.1186/s40824-022-00309-y

Internet

https://doi.org/10.1186/s40824-022-00309-y

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