Oral hydrogel microspheres were used for highly specific delivery of Steamed Codonopsis lanceolata to exert the protective effects on cisplatin-induced acute kidney injury in mice

Oral hydrogel microspheres were used for highly specific delivery of Steamed Codonopsis lanceolata to exert the protective effects on cisplatin-induced acute kidney injury in mice

Although Steamed Codonopsis lanceolata (SCL) has been shown to protect against acute kidney injury (AKI), Its poor stability and susceptibility to decomposition in the GI tract significantly reducing its therapeutic efficacy. Nanoscale/microscale drug delivery systems may overcome the difficulties o...

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Bibliographic Details
Main Authors: Yan-fei Li, Wei Li, Jun-nan Hu, Hui Shi, Qiong Shen, Shi-han Wang, Shuang Jiang, Yong-bo Liu, Li-chun Zhao, Zi Wang
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:Journal of Functional Foods
Subjects:
Steamed codonopsis lanceolata
Nephrotoxicity
Acute kidney injury
Cisplatin
Oral administration
Microparticles
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464623000312

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