Isoforms of U1-70k control subunit dynamics in the human spliceosomal U1 snRNP.

Most human protein-encoding genes contain multiple exons that are spliced together, frequently in alternative arrangements, by the spliceosome. It is established that U1 snRNP is an essential component of the spliceosome, in human consisting of RNA and ten proteins, several of which are post-transla...

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Bibliographic Details
Main Authors: Helena Hernández, Olga V Makarova, Evgeny M Makarov, Nina Morgner, Yutaka Muto, Daniel Pomeranz Krummel, Carol V Robinson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-09-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2747018?pdf=render