Prevalence, awareness, treatment and control of dyslipidemia in older persons in urban and rural population in the Astana region, Kazakhstan

Abstract Background Despite high cardiovascular mortality in Central Asian republics of the former Soviet Union, there is limited information about major risk factors, including blood lipids. We investigated the prevalence of impaired concentrations of blood lipids, the awareness, treatment and cont...

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Main Authors: Adil Supiyev, Talgat Nurgozhin, Zhaxybay Zhumadilov, Anne Peasey, Jaroslav A. Hubacek, Martin Bobak
Format: Article
Language:English
Published: BMC 2017-08-01
Series:BMC Public Health
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12889-017-4629-5
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author Adil Supiyev
Talgat Nurgozhin
Zhaxybay Zhumadilov
Anne Peasey
Jaroslav A. Hubacek
Martin Bobak
author_facet Adil Supiyev
Talgat Nurgozhin
Zhaxybay Zhumadilov
Anne Peasey
Jaroslav A. Hubacek
Martin Bobak
author_sort Adil Supiyev
collection DOAJ
description Abstract Background Despite high cardiovascular mortality in Central Asian republics of the former Soviet Union, there is limited information about major risk factors, including blood lipids. We investigated the prevalence of impaired concentrations of blood lipids, the awareness, treatment and control of hypercholesterolemia, and factors associated with these indicators in urban and rural populations in Kazakhstan. Methods We conducted a cross-sectional study of random urban and rural population samples (the state capital Astana and Akmol village). Men and women aged 50–74 years were examined; a total of 954 adults participated (response rate 59%). Serum concentrations of total, LDL and HDL cholesterol and triglycerides and a range of other cardiovascular risk factors were measured. Results The overall prevalence of hypercholesterolemia (total cholesterol ≥6.2 mmol/l) was 37%; among subjects with hypercholesterolemia, 57% were aware of their condition, 41% took medication and 23% had total cholesterol <6.2 mmol/l (4.5% <5 mmol/l). The prevalence, awareness, treatment, and control of hypercholesterolemia were all higher in the urban than the rural area. Similarly, the proportions of subjects with impaired concentrations of specific lipids fractions were also considerably higher in the urban population. Most associations with other covariates were in the expected direction. Conclusions This study found relatively high prevalence of dyslipidemia in the Kazakh population, and the blood lipid profile was less favourable in the urban area. These pronounced urban–rural differences may be related to urbanization, the associated nutrition transition and to access to health care.
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spelling doaj.art-7a5cd09d170349c68a7e3f890cdd4f952022-12-21T19:19:32ZengBMCBMC Public Health1471-24582017-08-011711910.1186/s12889-017-4629-5Prevalence, awareness, treatment and control of dyslipidemia in older persons in urban and rural population in the Astana region, KazakhstanAdil Supiyev0Talgat Nurgozhin1Zhaxybay Zhumadilov2Anne Peasey3Jaroslav A. Hubacek4Martin Bobak5Department of Epidemiology and Public Health, University College LondonLaboratory of Epidemiology and Public Health, Center for Life Sciences, PI National Laboratory Astana, Nazarbayev UniversityLaboratory of Epidemiology and Public Health, Center for Life Sciences, PI National Laboratory Astana, Nazarbayev UniversityDepartment of Epidemiology and Public Health, University College LondonCentre for Experimental Medicine, Institute of Clinical and Experimental MedicineDepartment of Epidemiology and Public Health, University College LondonAbstract Background Despite high cardiovascular mortality in Central Asian republics of the former Soviet Union, there is limited information about major risk factors, including blood lipids. We investigated the prevalence of impaired concentrations of blood lipids, the awareness, treatment and control of hypercholesterolemia, and factors associated with these indicators in urban and rural populations in Kazakhstan. Methods We conducted a cross-sectional study of random urban and rural population samples (the state capital Astana and Akmol village). Men and women aged 50–74 years were examined; a total of 954 adults participated (response rate 59%). Serum concentrations of total, LDL and HDL cholesterol and triglycerides and a range of other cardiovascular risk factors were measured. Results The overall prevalence of hypercholesterolemia (total cholesterol ≥6.2 mmol/l) was 37%; among subjects with hypercholesterolemia, 57% were aware of their condition, 41% took medication and 23% had total cholesterol <6.2 mmol/l (4.5% <5 mmol/l). The prevalence, awareness, treatment, and control of hypercholesterolemia were all higher in the urban than the rural area. Similarly, the proportions of subjects with impaired concentrations of specific lipids fractions were also considerably higher in the urban population. Most associations with other covariates were in the expected direction. Conclusions This study found relatively high prevalence of dyslipidemia in the Kazakh population, and the blood lipid profile was less favourable in the urban area. These pronounced urban–rural differences may be related to urbanization, the associated nutrition transition and to access to health care.http://link.springer.com/article/10.1186/s12889-017-4629-5HypercholesterolemiaDyslipidemiaSocioeconomic factorsCentral Asian countriesKazakhstan
spellingShingle Adil Supiyev
Talgat Nurgozhin
Zhaxybay Zhumadilov
Anne Peasey
Jaroslav A. Hubacek
Martin Bobak
Prevalence, awareness, treatment and control of dyslipidemia in older persons in urban and rural population in the Astana region, Kazakhstan
BMC Public Health
Hypercholesterolemia
Dyslipidemia
Socioeconomic factors
Central Asian countries
Kazakhstan
title Prevalence, awareness, treatment and control of dyslipidemia in older persons in urban and rural population in the Astana region, Kazakhstan
title_full Prevalence, awareness, treatment and control of dyslipidemia in older persons in urban and rural population in the Astana region, Kazakhstan
title_fullStr Prevalence, awareness, treatment and control of dyslipidemia in older persons in urban and rural population in the Astana region, Kazakhstan
title_full_unstemmed Prevalence, awareness, treatment and control of dyslipidemia in older persons in urban and rural population in the Astana region, Kazakhstan
title_short Prevalence, awareness, treatment and control of dyslipidemia in older persons in urban and rural population in the Astana region, Kazakhstan
title_sort prevalence awareness treatment and control of dyslipidemia in older persons in urban and rural population in the astana region kazakhstan
topic Hypercholesterolemia
Dyslipidemia
Socioeconomic factors
Central Asian countries
Kazakhstan
url http://link.springer.com/article/10.1186/s12889-017-4629-5
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