Mature dendritic cell-derived dendrosomes swallow oxaliplatin-loaded nanoparticles to boost immunogenic chemotherapy and tumor antigen-specific immunotherapy

Mature dendritic cell-derived dendrosomes swallow oxaliplatin-loaded nanoparticles to boost immunogenic chemotherapy and tumor antigen-specific immunotherapy

The cytomembrane-derived delivery platform represents a promising biomimetic strategy in oncotherapy. To achieve durable and reliable tumor inhibition, mature dendrosomes (mDs), which were isolated from bone marrow-derived dendritic cells undergoing CT26 tumor antigen (TA) stimulation, were fused wi...

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Bibliographic Details
Main Authors: Xing Chen, Xiang Ling, Jiaxuan Xia, Ying Zhu, Longlong Zhang, Yuwei He, Anni Wang, Guolong Gu, Bo Yin, Jianxin Wang
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2022-09-01
Series:Bioactive Materials
Subjects:
Dendritic cell
Dendrosome
Antigen delivery
Immunotherapy
Chemotherapy
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X21005946

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