Safety, effectiveness, and adherence of a short and all-oral treatment regimen for the treatment of rifampicin-resistant tuberculosis in Niger: a study protocol of a pragmatic randomised clinical trial with stratified block randomisation

Safety, effectiveness, and adherence of a short and all-oral treatment regimen for the treatment of rifampicin-resistant tuberculosis in Niger: a study protocol of a pragmatic randomised clinical trial with stratified block randomisation

Abstract Background Rifampicin-resistant tuberculosis (RR-TB) treatment requires combination treatment, which frequently causes serious adverse events and globally results in not much more than 60% treatment success. In Niger, a high cure rate was obtained with a RR-TB treatment strategy based on a...

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Bibliographic Details
Main Authors: Mahamadou Bassirou Souleymane, Tom Decroo, Alphazazi Soumana, Ibrahim Maman Lawan, Assiatou Gagara-Issoufou, Souleymane Halidou-Moussa, Nimer Ortuño-Gutiérrez, Eric Adehossi, Saïdou Mamadou, Armand Van Deun, Alberto Piubello
Format: Article
Language:English
Published: BMC 2022-12-01
Series:Trials
Subjects:
Rifampicin resistance tuberculosis
All oral treatment
New anti-tuberculosis drugs
Niger
Online Access:https://doi.org/10.1186/s13063-022-06912-7

Internet

https://doi.org/10.1186/s13063-022-06912-7

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