Haemagglutinin antigen selectively targeted to chicken CD83 overcomes interference from maternally derived antibodies in chickens

Abstract Maternally derived antibodies (MDAs) are important for protecting chickens against pathogens in the neonatal stage however, they often interfere with vaccine performance. Here, we investigated the effects of MDAs on a targeted antigen delivery vaccine (TADV), which is developed by conjugati...

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Bibliographic Details
Main Authors: Angita Shrestha, Rick Meeuws, Jean-Remy Sadeyen, Pengxiang Chang, Marielle Van Hulten, Munir Iqbal
Format: Article
Language:English
Published: Nature Portfolio 2022-03-01
Series:npj Vaccines
Online Access:https://doi.org/10.1038/s41541-022-00448-2

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