Sub-lobar dysplasia — A comprehensive evaluation with neuroimaging, magnetoencephalography and histopathology
Sublobar dysplasia, a rare cortical malformation has been defined in only 8 patients to date. It was identified on the basis of histopathological features and MRI findings. We report a right temporal sublobar dysplasia, with detailed evaluation including neuroimaging, magnetoencephalography and hist...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2018-01-01
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| Series: | Epilepsy and Behavior Case Reports |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2213323217301196 |
| _version_ | 1819147912150515712 |
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| author | Kenchaiah Raghavendra Ganne Chaitanya Bhargava Goutham Anita Mahadevan Ravindranadh Chowdary Mundlamuri Rose Dawn Bharath Mariyappa Narayannan Malla Bhaskar Rao Arimappamagan Arivazhagan Parthasarthy Satishchandra Sanjib Sinha |
| author_facet | Kenchaiah Raghavendra Ganne Chaitanya Bhargava Goutham Anita Mahadevan Ravindranadh Chowdary Mundlamuri Rose Dawn Bharath Mariyappa Narayannan Malla Bhaskar Rao Arimappamagan Arivazhagan Parthasarthy Satishchandra Sanjib Sinha |
| author_sort | Kenchaiah Raghavendra |
| collection | DOAJ |
| description | Sublobar dysplasia, a rare cortical malformation has been defined in only 8 patients to date. It was identified on the basis of histopathological features and MRI findings. We report a right temporal sublobar dysplasia, with detailed evaluation including neuroimaging, magnetoencephalography and histopathology to further characterize the pathology. Additional pathological features included a deep collateral sulcus in the basal right temporal lobe, thinned out right corticospinal tract, and bilateral asymmetric basal ganglia changes. Magnetoencephalograpy localized the seizure focus to the posterior margin of the dysplasia. Histopathological evaluation helped exclude other types of dysplasia. Similar to a previous study, the child had Engel 1a outcome. Keywords: Sublobar dysplasia, Temporal lobe epilepsy, Tractography, Magnetoencephalography, Histopathology |
| first_indexed | 2024-12-22T13:37:21Z |
| format | Article |
| id | doaj.art-7a6868c4158e42c6be5f0fc81bd5f79b |
| institution | Directory Open Access Journal |
| issn | 2213-3232 |
| language | English |
| last_indexed | 2024-12-22T13:37:21Z |
| publishDate | 2018-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Epilepsy and Behavior Case Reports |
| spelling | doaj.art-7a6868c4158e42c6be5f0fc81bd5f79b2022-12-21T18:24:01ZengElsevierEpilepsy and Behavior Case Reports2213-32322018-01-0192225Sub-lobar dysplasia — A comprehensive evaluation with neuroimaging, magnetoencephalography and histopathologyKenchaiah Raghavendra0Ganne Chaitanya1Bhargava Goutham2Anita Mahadevan3Ravindranadh Chowdary Mundlamuri4Rose Dawn Bharath5Mariyappa Narayannan6Malla Bhaskar Rao7Arimappamagan Arivazhagan8Parthasarthy Satishchandra9Sanjib Sinha10Department of Neurology, National Institute of Mental Health and Neurosciences (NIMHANS), Hosur Road, Bangalore 560029, IndiaDepartment of Neurology, National Institute of Mental Health and Neurosciences (NIMHANS), Hosur Road, Bangalore 560029, India; Department of Clinical Neurosciences, National Institute of Mental Health and Neurosciences (NIMHANS), Hosur Road, Bangalore 560029, IndiaDepartment of Neurology, National Institute of Mental Health and Neurosciences (NIMHANS), Hosur Road, Bangalore 560029, India; Department of Clinical Neurosciences, National Institute of Mental Health and Neurosciences (NIMHANS), Hosur Road, Bangalore 560029, IndiaDepartment of Neuropathology, National Institute of Mental Health and Neurosciences (NIMHANS), Hosur Road, Bangalore 560029, IndiaDepartment of Neurology, National Institute of Mental Health and Neurosciences (NIMHANS), Hosur Road, Bangalore 560029, IndiaDepartment of Neuroimaging and Interventional Radiology, National Institute of Mental Health and Neurosciences (NIMHANS), Hosur Road, Bangalore 560029, IndiaDepartment of Neurology, National Institute of Mental Health and Neurosciences (NIMHANS), Hosur Road, Bangalore 560029, IndiaDepartment of Neurosurgery, National Institute of Mental Health and Neurosciences (NIMHANS), Hosur Road, Bangalore 560029, IndiaDepartment of Neurosurgery, National Institute of Mental Health and Neurosciences (NIMHANS), Hosur Road, Bangalore 560029, IndiaDepartment of Neurology, National Institute of Mental Health and Neurosciences (NIMHANS), Hosur Road, Bangalore 560029, IndiaDepartment of Neurology, National Institute of Mental Health and Neurosciences (NIMHANS), Hosur Road, Bangalore 560029, India; Corresponding author at: NIMHANS, 1st Floor, Faculty Block, Hosur Road, Bangalore 560029, India.Sublobar dysplasia, a rare cortical malformation has been defined in only 8 patients to date. It was identified on the basis of histopathological features and MRI findings. We report a right temporal sublobar dysplasia, with detailed evaluation including neuroimaging, magnetoencephalography and histopathology to further characterize the pathology. Additional pathological features included a deep collateral sulcus in the basal right temporal lobe, thinned out right corticospinal tract, and bilateral asymmetric basal ganglia changes. Magnetoencephalograpy localized the seizure focus to the posterior margin of the dysplasia. Histopathological evaluation helped exclude other types of dysplasia. Similar to a previous study, the child had Engel 1a outcome. Keywords: Sublobar dysplasia, Temporal lobe epilepsy, Tractography, Magnetoencephalography, Histopathologyhttp://www.sciencedirect.com/science/article/pii/S2213323217301196 |
| spellingShingle | Kenchaiah Raghavendra Ganne Chaitanya Bhargava Goutham Anita Mahadevan Ravindranadh Chowdary Mundlamuri Rose Dawn Bharath Mariyappa Narayannan Malla Bhaskar Rao Arimappamagan Arivazhagan Parthasarthy Satishchandra Sanjib Sinha Sub-lobar dysplasia — A comprehensive evaluation with neuroimaging, magnetoencephalography and histopathology Epilepsy and Behavior Case Reports |
| title | Sub-lobar dysplasia — A comprehensive evaluation with neuroimaging, magnetoencephalography and histopathology |
| title_full | Sub-lobar dysplasia — A comprehensive evaluation with neuroimaging, magnetoencephalography and histopathology |
| title_fullStr | Sub-lobar dysplasia — A comprehensive evaluation with neuroimaging, magnetoencephalography and histopathology |
| title_full_unstemmed | Sub-lobar dysplasia — A comprehensive evaluation with neuroimaging, magnetoencephalography and histopathology |
| title_short | Sub-lobar dysplasia — A comprehensive evaluation with neuroimaging, magnetoencephalography and histopathology |
| title_sort | sub lobar dysplasia a comprehensive evaluation with neuroimaging magnetoencephalography and histopathology |
| url | http://www.sciencedirect.com/science/article/pii/S2213323217301196 |
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