Intracameral Microimaging of Maturation of Human iPSC Derivatives into Islet Endocrine Cells

Intracameral Microimaging of Maturation of Human iPSC Derivatives into Islet Endocrine Cells

We exploited the anterior chamber of the eye (ACE) of immunodeficient mice as an ectopic site for both transplantation and microimaging of engineered surrogate islets from human induced pluripotent stem cells (hiPSC-SIs). These islets contained a majority of insulin-expressing cells, positive or neg...

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Bibliographic Details
Main Authors: Kaixuan Zhao, Yue Shi, Jia Yu, Lina Yu, Amber Mael, Yuxin Li, Anthony Kolton, Thomas Joyce, Jon Odorico, Per-Olof Berggren, Shao-Nian Yang
Format: Article
Language:English
Published: SAGE Publishing 2022-01-01
Series:Cell Transplantation
Online Access:https://doi.org/10.1177/09636897211066508

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