A RETROSPECTIVE CROSS-SECTIONAL STUDY INVESTIGATING THE PREVALENCE OF COVID-19 AND TB COINFECTION IN PATIENTS IN KWAZULU-NATAL, SOUTH AFRICA.
Background: The co-occurrence of tuberculosis (TB) and Covid-19 pose significant challenges to public health systems worldwide. This study aimed to investigate the prevalence of TB and Covid- 19 co-infection, explore the correlation between TB status and Covid-19 results and examine the distributi...
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| Format: | Article |
| Language: | English |
| Published: |
Student's Journal of Health Research
2023-06-01
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| Series: | Student's Journal of Health Research Africa |
| Subjects: | |
| Online Access: | https://sjhresearchafrica.org/index.php/public-html/article/view/416 |
| _version_ | 1797791317900656640 |
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| author | Vuyo Hlabisa Ziningi Nobuhle Jaya |
| author_facet | Vuyo Hlabisa Ziningi Nobuhle Jaya |
| author_sort | Vuyo Hlabisa |
| collection | DOAJ |
| description |
Background:
The co-occurrence of tuberculosis (TB) and Covid-19 pose significant challenges to public
health systems worldwide. This study aimed to investigate the prevalence of TB and Covid-
19 co-infection, explore the correlation between TB status and Covid-19 results and examine
the distribution of co-infection across different age groups in KwaZulu-Natal, South Africa.
Methods:
A retrospective analysis was conducted using data retrieved from a laboratory database,
including 1241 TB patient results between April 2020 and April 2021. Diagnostic methods
for TB included microscopy, culture, GeneXpert, and line probe. Covid-19 test results were
categorized as positive, negative, or inconclusive. Statistical analysis, including statistical
significance tests, was performed to assess the correlation between TB status, Covid-19 co-
infection, and age groups.
Results:
Among the TB patients, 3.95% were diagnosed using microscopy, 7.01% using culture,
88.80% using GeneXpert, and 0.24% using line probe. Out of the 1241 TB patients, 50%
were males and 49% were females. Among the tested patients, 84% tested negative for Covid-19, 14.5% tested positive, and 1% had inconclusive findings. The statistical
significance analysis indicated no significant correlation between TB status and Covid-19 co-
infection (p > 0.05). However, a significant association was observed between age groups and Covid-19 co-infection (p < 0.05).
Conclusion:
Although no significant correlation was found between TB status and Covid-19 co-infection, there was a significant association between age groups and co-infection rates. These findings highlight the need for tailored screening, prevention, and treatment strategies considering different age groups. The study contributes to the existing literature and can inform healthcare policies and interventions related to TB and Covid-19 co-infection.
Recommendation:
To address the co-infection, we recommend strengthening surveillance, enhancing awareness, conducting further research, improving infection control, and developing integrated healthcare approaches.
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| first_indexed | 2024-03-13T02:17:04Z |
| format | Article |
| id | doaj.art-7a6ddff2d7684af7bdf5173a3808c12c |
| institution | Directory Open Access Journal |
| issn | 2709-9997 |
| language | English |
| last_indexed | 2024-03-13T02:17:04Z |
| publishDate | 2023-06-01 |
| publisher | Student's Journal of Health Research |
| record_format | Article |
| series | Student's Journal of Health Research Africa |
| spelling | doaj.art-7a6ddff2d7684af7bdf5173a3808c12c2023-06-30T11:43:33ZengStudent's Journal of Health ResearchStudent's Journal of Health Research Africa2709-99972023-06-014610.51168/sjhrafrica.v4i6.416A RETROSPECTIVE CROSS-SECTIONAL STUDY INVESTIGATING THE PREVALENCE OF COVID-19 AND TB COINFECTION IN PATIENTS IN KWAZULU-NATAL, SOUTH AFRICA.Vuyo Hlabisa0Ziningi Nobuhle Jaya1 Department of Biomedical Science, Faculty of Natural Science, Mangosuthu University of Technology, KwaZulu-Natal, South Africa.Mangosuthu University of Technology Background: The co-occurrence of tuberculosis (TB) and Covid-19 pose significant challenges to public health systems worldwide. This study aimed to investigate the prevalence of TB and Covid- 19 co-infection, explore the correlation between TB status and Covid-19 results and examine the distribution of co-infection across different age groups in KwaZulu-Natal, South Africa. Methods: A retrospective analysis was conducted using data retrieved from a laboratory database, including 1241 TB patient results between April 2020 and April 2021. Diagnostic methods for TB included microscopy, culture, GeneXpert, and line probe. Covid-19 test results were categorized as positive, negative, or inconclusive. Statistical analysis, including statistical significance tests, was performed to assess the correlation between TB status, Covid-19 co- infection, and age groups. Results: Among the TB patients, 3.95% were diagnosed using microscopy, 7.01% using culture, 88.80% using GeneXpert, and 0.24% using line probe. Out of the 1241 TB patients, 50% were males and 49% were females. Among the tested patients, 84% tested negative for Covid-19, 14.5% tested positive, and 1% had inconclusive findings. The statistical significance analysis indicated no significant correlation between TB status and Covid-19 co- infection (p > 0.05). However, a significant association was observed between age groups and Covid-19 co-infection (p < 0.05). Conclusion: Although no significant correlation was found between TB status and Covid-19 co-infection, there was a significant association between age groups and co-infection rates. These findings highlight the need for tailored screening, prevention, and treatment strategies considering different age groups. The study contributes to the existing literature and can inform healthcare policies and interventions related to TB and Covid-19 co-infection. Recommendation: To address the co-infection, we recommend strengthening surveillance, enhancing awareness, conducting further research, improving infection control, and developing integrated healthcare approaches. https://sjhresearchafrica.org/index.php/public-html/article/view/416Turberculosisco-infectionCovid-19prevalencecorrelationage group |
| spellingShingle | Vuyo Hlabisa Ziningi Nobuhle Jaya A RETROSPECTIVE CROSS-SECTIONAL STUDY INVESTIGATING THE PREVALENCE OF COVID-19 AND TB COINFECTION IN PATIENTS IN KWAZULU-NATAL, SOUTH AFRICA. Student's Journal of Health Research Africa Turberculosis co-infection Covid-19 prevalence correlation age group |
| title | A RETROSPECTIVE CROSS-SECTIONAL STUDY INVESTIGATING THE PREVALENCE OF COVID-19 AND TB COINFECTION IN PATIENTS IN KWAZULU-NATAL, SOUTH AFRICA. |
| title_full | A RETROSPECTIVE CROSS-SECTIONAL STUDY INVESTIGATING THE PREVALENCE OF COVID-19 AND TB COINFECTION IN PATIENTS IN KWAZULU-NATAL, SOUTH AFRICA. |
| title_fullStr | A RETROSPECTIVE CROSS-SECTIONAL STUDY INVESTIGATING THE PREVALENCE OF COVID-19 AND TB COINFECTION IN PATIENTS IN KWAZULU-NATAL, SOUTH AFRICA. |
| title_full_unstemmed | A RETROSPECTIVE CROSS-SECTIONAL STUDY INVESTIGATING THE PREVALENCE OF COVID-19 AND TB COINFECTION IN PATIENTS IN KWAZULU-NATAL, SOUTH AFRICA. |
| title_short | A RETROSPECTIVE CROSS-SECTIONAL STUDY INVESTIGATING THE PREVALENCE OF COVID-19 AND TB COINFECTION IN PATIENTS IN KWAZULU-NATAL, SOUTH AFRICA. |
| title_sort | retrospective cross sectional study investigating the prevalence of covid 19 and tb coinfection in patients in kwazulu natal south africa |
| topic | Turberculosis co-infection Covid-19 prevalence correlation age group |
| url | https://sjhresearchafrica.org/index.php/public-html/article/view/416 |
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