SGK1 is essential for meiotic resumption in mammalian oocytes

SGK1 is essential for meiotic resumption in mammalian oocytes

In mammalian females, oocytes are stored in the ovary and meiosis is arrested at the diplotene stage of prophase I. When females reach puberty oocytes are selectively recruited in cycles to grow, overcome the meiotic arrest, complete the first meiotic division and become mature (ready for fertilizat...

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Bibliographic Details
Main Authors: Edgar del Llano, Rajan Iyyappan, Daria Aleshkina, Tomas Masek, Michal Dvoran, Zongliang Jiang, Martin Pospisek, Michal Kubelka, Andrej Susor
Format: Article
Language:English
Published: Elsevier 2022-04-01
Series:European Journal of Cell Biology
Subjects:
Oocyte
MPF
CDK1
SGK1
Meiosis
Nuclear envelope breakdown
Online Access:http://www.sciencedirect.com/science/article/pii/S0171933522000139

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