Outcome of total hip arthroplasty, but not of total knee arthroplasty, is related to the preoperative radiographic severity of osteoarthritis: A prospective cohort study of 573 patients
Background and purpose — There is no consensus on the impact of radiographic severity of hip and knee osteoarthritis (OA) on the clinical outcome of total hip arthroplasty (THA) and total knee arthroplasty (TKA). We assessed whether preoperative radiographic severity of OA is related to improvements...
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Format: | Article |
Language: | English |
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Medical Journals Sweden
2016-01-01
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Series: | Acta Orthopaedica |
Online Access: | http://dx.doi.org/10.3109/17453674.2015.1092369 |
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author | Claire Tilbury Maarten J Holtslag Rutger L Tordoir Claudia S Leichtenberg Suzan H M Verdegaal Herman M Kroon Marta Fiocco Rob G H H Nelissen Thea P M Vliet Vlieland |
author_facet | Claire Tilbury Maarten J Holtslag Rutger L Tordoir Claudia S Leichtenberg Suzan H M Verdegaal Herman M Kroon Marta Fiocco Rob G H H Nelissen Thea P M Vliet Vlieland |
author_sort | Claire Tilbury |
collection | DOAJ |
description | Background and purpose — There is no consensus on the impact of radiographic severity of hip and knee osteoarthritis (OA) on the clinical outcome of total hip arthroplasty (THA) and total knee arthroplasty (TKA). We assessed whether preoperative radiographic severity of OA is related to improvements in functioning, pain, and health-related quality of life (HRQoL) 1 year after THA or TKA. Patients and methods — This prospective cohort study included 302 THA patients and 271 TKA patients with hip or knee OA. In the THA patients, preoperatively 26% had mild OA and 74% had severe OA; in the TKA patients, preoperatively 27% had mild OA and 73% had severe OA. Radiographic severity was determined according to the Kellgren and Lawrence (KL) classification. Clinical assessments preoperatively and 1 year postoperatively included: sociodemographic characteristics and patient-reported outcomes (PROMs): Oxford hip/knee score, hip/knee injury and osteoarthritis outcome score (HOOS/KOOS), SF36, and EQ5D. Change scores of PROMs were compared with mild OA (KL 0–2) and severe OA (KL 3–4) using a multivariate linear regression model. Results — Adjusted for sex, age, preoperative scores, BMI, and Charnley score, radiographic severity of OA in THA was associated with improvement in HOOS “Activities of daily living”, “Pain”, and “Symptoms”, and SF36 physical component summary (“PCS”) scale. In TKA, we found no such associations. Interpretation — The decrease in pain and improvement in function in THA patients, but not in TKA patients, was positively associated with the preoperative radiographic severity of OA. |
first_indexed | 2024-12-24T19:15:02Z |
format | Article |
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institution | Directory Open Access Journal |
issn | 1745-3674 1745-3682 |
language | English |
last_indexed | 2024-12-24T19:15:02Z |
publishDate | 2016-01-01 |
publisher | Medical Journals Sweden |
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series | Acta Orthopaedica |
spelling | doaj.art-7a750c04004a4741b48b0ad431fd43cd2022-12-21T16:42:54ZengMedical Journals SwedenActa Orthopaedica1745-36741745-36822016-01-01871677110.3109/17453674.2015.10923691092369Outcome of total hip arthroplasty, but not of total knee arthroplasty, is related to the preoperative radiographic severity of osteoarthritis: A prospective cohort study of 573 patientsClaire Tilbury0Maarten J Holtslag1Rutger L Tordoir2Claudia S Leichtenberg3Suzan H M Verdegaal4Herman M Kroon5Marta Fiocco6Rob G H H Nelissen7Thea P M Vliet Vlieland8Leiden University Medical CenterLeiden University Medical CenterRijnland HospitalLeiden University Medical CenterRijnland HospitalLeiden University Medical CenterLeiden University Medical CenterLeiden University Medical CenterLeiden University Medical CenterBackground and purpose — There is no consensus on the impact of radiographic severity of hip and knee osteoarthritis (OA) on the clinical outcome of total hip arthroplasty (THA) and total knee arthroplasty (TKA). We assessed whether preoperative radiographic severity of OA is related to improvements in functioning, pain, and health-related quality of life (HRQoL) 1 year after THA or TKA. Patients and methods — This prospective cohort study included 302 THA patients and 271 TKA patients with hip or knee OA. In the THA patients, preoperatively 26% had mild OA and 74% had severe OA; in the TKA patients, preoperatively 27% had mild OA and 73% had severe OA. Radiographic severity was determined according to the Kellgren and Lawrence (KL) classification. Clinical assessments preoperatively and 1 year postoperatively included: sociodemographic characteristics and patient-reported outcomes (PROMs): Oxford hip/knee score, hip/knee injury and osteoarthritis outcome score (HOOS/KOOS), SF36, and EQ5D. Change scores of PROMs were compared with mild OA (KL 0–2) and severe OA (KL 3–4) using a multivariate linear regression model. Results — Adjusted for sex, age, preoperative scores, BMI, and Charnley score, radiographic severity of OA in THA was associated with improvement in HOOS “Activities of daily living”, “Pain”, and “Symptoms”, and SF36 physical component summary (“PCS”) scale. In TKA, we found no such associations. Interpretation — The decrease in pain and improvement in function in THA patients, but not in TKA patients, was positively associated with the preoperative radiographic severity of OA.http://dx.doi.org/10.3109/17453674.2015.1092369 |
spellingShingle | Claire Tilbury Maarten J Holtslag Rutger L Tordoir Claudia S Leichtenberg Suzan H M Verdegaal Herman M Kroon Marta Fiocco Rob G H H Nelissen Thea P M Vliet Vlieland Outcome of total hip arthroplasty, but not of total knee arthroplasty, is related to the preoperative radiographic severity of osteoarthritis: A prospective cohort study of 573 patients Acta Orthopaedica |
title | Outcome of total hip arthroplasty, but not of total knee arthroplasty, is related to the preoperative radiographic severity of osteoarthritis: A prospective cohort study of 573 patients |
title_full | Outcome of total hip arthroplasty, but not of total knee arthroplasty, is related to the preoperative radiographic severity of osteoarthritis: A prospective cohort study of 573 patients |
title_fullStr | Outcome of total hip arthroplasty, but not of total knee arthroplasty, is related to the preoperative radiographic severity of osteoarthritis: A prospective cohort study of 573 patients |
title_full_unstemmed | Outcome of total hip arthroplasty, but not of total knee arthroplasty, is related to the preoperative radiographic severity of osteoarthritis: A prospective cohort study of 573 patients |
title_short | Outcome of total hip arthroplasty, but not of total knee arthroplasty, is related to the preoperative radiographic severity of osteoarthritis: A prospective cohort study of 573 patients |
title_sort | outcome of total hip arthroplasty but not of total knee arthroplasty is related to the preoperative radiographic severity of osteoarthritis a prospective cohort study of 573 patients |
url | http://dx.doi.org/10.3109/17453674.2015.1092369 |
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