Outcome of total hip arthroplasty, but not of total knee arthroplasty, is related to the preoperative radiographic severity of osteoarthritis: A prospective cohort study of 573 patients

Background and purpose — There is no consensus on the impact of radiographic severity of hip and knee osteoarthritis (OA) on the clinical outcome of total hip arthroplasty (THA) and total knee arthroplasty (TKA). We assessed whether preoperative radiographic severity of OA is related to improvements...

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Main Authors: Claire Tilbury, Maarten J Holtslag, Rutger L Tordoir, Claudia S Leichtenberg, Suzan H M Verdegaal, Herman M Kroon, Marta Fiocco, Rob G H H Nelissen, Thea P M Vliet Vlieland
Format: Article
Language:English
Published: Medical Journals Sweden 2016-01-01
Series:Acta Orthopaedica
Online Access:http://dx.doi.org/10.3109/17453674.2015.1092369
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author Claire Tilbury
Maarten J Holtslag
Rutger L Tordoir
Claudia S Leichtenberg
Suzan H M Verdegaal
Herman M Kroon
Marta Fiocco
Rob G H H Nelissen
Thea P M Vliet Vlieland
author_facet Claire Tilbury
Maarten J Holtslag
Rutger L Tordoir
Claudia S Leichtenberg
Suzan H M Verdegaal
Herman M Kroon
Marta Fiocco
Rob G H H Nelissen
Thea P M Vliet Vlieland
author_sort Claire Tilbury
collection DOAJ
description Background and purpose — There is no consensus on the impact of radiographic severity of hip and knee osteoarthritis (OA) on the clinical outcome of total hip arthroplasty (THA) and total knee arthroplasty (TKA). We assessed whether preoperative radiographic severity of OA is related to improvements in functioning, pain, and health-related quality of life (HRQoL) 1 year after THA or TKA. Patients and methods — This prospective cohort study included 302 THA patients and 271 TKA patients with hip or knee OA. In the THA patients, preoperatively 26% had mild OA and 74% had severe OA; in the TKA patients, preoperatively 27% had mild OA and 73% had severe OA. Radiographic severity was determined according to the Kellgren and Lawrence (KL) classification. Clinical assessments preoperatively and 1 year postoperatively included: sociodemographic characteristics and patient-reported outcomes (PROMs): Oxford hip/knee score, hip/knee injury and osteoarthritis outcome score (HOOS/KOOS), SF36, and EQ5D. Change scores of PROMs were compared with mild OA (KL 0–2) and severe OA (KL 3–4) using a multivariate linear regression model. Results — Adjusted for sex, age, preoperative scores, BMI, and Charnley score, radiographic severity of OA in THA was associated with improvement in HOOS “Activities of daily living”, “Pain”, and “Symptoms”, and SF36 physical component summary (“PCS”) scale. In TKA, we found no such associations. Interpretation — The decrease in pain and improvement in function in THA patients, but not in TKA patients, was positively associated with the preoperative radiographic severity of OA.
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spelling doaj.art-7a750c04004a4741b48b0ad431fd43cd2022-12-21T16:42:54ZengMedical Journals SwedenActa Orthopaedica1745-36741745-36822016-01-01871677110.3109/17453674.2015.10923691092369Outcome of total hip arthroplasty, but not of total knee arthroplasty, is related to the preoperative radiographic severity of osteoarthritis: A prospective cohort study of 573 patientsClaire Tilbury0Maarten J Holtslag1Rutger L Tordoir2Claudia S Leichtenberg3Suzan H M Verdegaal4Herman M Kroon5Marta Fiocco6Rob G H H Nelissen7Thea P M Vliet Vlieland8Leiden University Medical CenterLeiden University Medical CenterRijnland HospitalLeiden University Medical CenterRijnland HospitalLeiden University Medical CenterLeiden University Medical CenterLeiden University Medical CenterLeiden University Medical CenterBackground and purpose — There is no consensus on the impact of radiographic severity of hip and knee osteoarthritis (OA) on the clinical outcome of total hip arthroplasty (THA) and total knee arthroplasty (TKA). We assessed whether preoperative radiographic severity of OA is related to improvements in functioning, pain, and health-related quality of life (HRQoL) 1 year after THA or TKA. Patients and methods — This prospective cohort study included 302 THA patients and 271 TKA patients with hip or knee OA. In the THA patients, preoperatively 26% had mild OA and 74% had severe OA; in the TKA patients, preoperatively 27% had mild OA and 73% had severe OA. Radiographic severity was determined according to the Kellgren and Lawrence (KL) classification. Clinical assessments preoperatively and 1 year postoperatively included: sociodemographic characteristics and patient-reported outcomes (PROMs): Oxford hip/knee score, hip/knee injury and osteoarthritis outcome score (HOOS/KOOS), SF36, and EQ5D. Change scores of PROMs were compared with mild OA (KL 0–2) and severe OA (KL 3–4) using a multivariate linear regression model. Results — Adjusted for sex, age, preoperative scores, BMI, and Charnley score, radiographic severity of OA in THA was associated with improvement in HOOS “Activities of daily living”, “Pain”, and “Symptoms”, and SF36 physical component summary (“PCS”) scale. In TKA, we found no such associations. Interpretation — The decrease in pain and improvement in function in THA patients, but not in TKA patients, was positively associated with the preoperative radiographic severity of OA.http://dx.doi.org/10.3109/17453674.2015.1092369
spellingShingle Claire Tilbury
Maarten J Holtslag
Rutger L Tordoir
Claudia S Leichtenberg
Suzan H M Verdegaal
Herman M Kroon
Marta Fiocco
Rob G H H Nelissen
Thea P M Vliet Vlieland
Outcome of total hip arthroplasty, but not of total knee arthroplasty, is related to the preoperative radiographic severity of osteoarthritis: A prospective cohort study of 573 patients
Acta Orthopaedica
title Outcome of total hip arthroplasty, but not of total knee arthroplasty, is related to the preoperative radiographic severity of osteoarthritis: A prospective cohort study of 573 patients
title_full Outcome of total hip arthroplasty, but not of total knee arthroplasty, is related to the preoperative radiographic severity of osteoarthritis: A prospective cohort study of 573 patients
title_fullStr Outcome of total hip arthroplasty, but not of total knee arthroplasty, is related to the preoperative radiographic severity of osteoarthritis: A prospective cohort study of 573 patients
title_full_unstemmed Outcome of total hip arthroplasty, but not of total knee arthroplasty, is related to the preoperative radiographic severity of osteoarthritis: A prospective cohort study of 573 patients
title_short Outcome of total hip arthroplasty, but not of total knee arthroplasty, is related to the preoperative radiographic severity of osteoarthritis: A prospective cohort study of 573 patients
title_sort outcome of total hip arthroplasty but not of total knee arthroplasty is related to the preoperative radiographic severity of osteoarthritis a prospective cohort study of 573 patients
url http://dx.doi.org/10.3109/17453674.2015.1092369
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