Recent Advances in Antiviral Activities of Triterpenoids
Triterpenoids, important secondary plant metabolites made up of six isoprene units, are found widely in higher plants and are studied for their structural variety and wide range of bioactivities, including antiviral, antioxidant, anticancer, and anti-inflammatory properties. Numerous studies have de...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-09-01
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| Series: | Pharmaceuticals |
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| Online Access: | https://www.mdpi.com/1424-8247/15/10/1169 |
| _version_ | 1827648391136411648 |
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| author | Yue Liu Liangyu Yang Hong Wang Yongai Xiong |
| author_facet | Yue Liu Liangyu Yang Hong Wang Yongai Xiong |
| author_sort | Yue Liu |
| collection | DOAJ |
| description | Triterpenoids, important secondary plant metabolites made up of six isoprene units, are found widely in higher plants and are studied for their structural variety and wide range of bioactivities, including antiviral, antioxidant, anticancer, and anti-inflammatory properties. Numerous studies have demonstrated that different triterpenoids have the potential to behave as potential antiviral agents. The antiviral activities of triterpenoids and their derivatives are summarized in this review, with examples of oleanane, ursane, lupane, dammarane, lanostane, and cycloartane triterpenoids. We concentrated on the tetracyclic and pentacyclic triterpenoids in particular. Furthermore, the particular viral types and possible methods, such as anti-human immunodeficiency virus (HIV), anti-influenza virus, and anti-hepatitis virus, are presented in this article. This review gives an overview and a discussion of triterpenoids as potential antiviral agents. |
| first_indexed | 2024-03-09T19:37:37Z |
| format | Article |
| id | doaj.art-7a7530e9ef19482b99046d19cfcbdb0e |
| institution | Directory Open Access Journal |
| issn | 1424-8247 |
| language | English |
| last_indexed | 2024-03-09T19:37:37Z |
| publishDate | 2022-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Pharmaceuticals |
| spelling | doaj.art-7a7530e9ef19482b99046d19cfcbdb0e2023-11-24T01:50:16ZengMDPI AGPharmaceuticals1424-82472022-09-011510116910.3390/ph15101169Recent Advances in Antiviral Activities of TriterpenoidsYue Liu0Liangyu Yang1Hong Wang2Yongai Xiong3Department of Pharmaceutics, Key Laboratory of Basic Pharmacology of Guizhou Province and School of Pharmacy, Zunyi Medical University, Zunyi 563000, ChinaDepartment of Pharmaceutics, Key Laboratory of Basic Pharmacology of Guizhou Province and School of Pharmacy, Zunyi Medical University, Zunyi 563000, ChinaDepartment of Pharmaceutics, Key Laboratory of Basic Pharmacology of Guizhou Province and School of Pharmacy, Zunyi Medical University, Zunyi 563000, ChinaDepartment of Pharmaceutics, Key Laboratory of Basic Pharmacology of Guizhou Province and School of Pharmacy, Zunyi Medical University, Zunyi 563000, ChinaTriterpenoids, important secondary plant metabolites made up of six isoprene units, are found widely in higher plants and are studied for their structural variety and wide range of bioactivities, including antiviral, antioxidant, anticancer, and anti-inflammatory properties. Numerous studies have demonstrated that different triterpenoids have the potential to behave as potential antiviral agents. The antiviral activities of triterpenoids and their derivatives are summarized in this review, with examples of oleanane, ursane, lupane, dammarane, lanostane, and cycloartane triterpenoids. We concentrated on the tetracyclic and pentacyclic triterpenoids in particular. Furthermore, the particular viral types and possible methods, such as anti-human immunodeficiency virus (HIV), anti-influenza virus, and anti-hepatitis virus, are presented in this article. This review gives an overview and a discussion of triterpenoids as potential antiviral agents.https://www.mdpi.com/1424-8247/15/10/1169terpenoidsbiological activitynatural products |
| spellingShingle | Yue Liu Liangyu Yang Hong Wang Yongai Xiong Recent Advances in Antiviral Activities of Triterpenoids Pharmaceuticals terpenoids biological activity natural products |
| title | Recent Advances in Antiviral Activities of Triterpenoids |
| title_full | Recent Advances in Antiviral Activities of Triterpenoids |
| title_fullStr | Recent Advances in Antiviral Activities of Triterpenoids |
| title_full_unstemmed | Recent Advances in Antiviral Activities of Triterpenoids |
| title_short | Recent Advances in Antiviral Activities of Triterpenoids |
| title_sort | recent advances in antiviral activities of triterpenoids |
| topic | terpenoids biological activity natural products |
| url | https://www.mdpi.com/1424-8247/15/10/1169 |
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