ADSC-derived exosomes attenuate myocardial infarction injury by promoting miR-205-mediated cardiac angiogenesis

ADSC-derived exosomes attenuate myocardial infarction injury by promoting miR-205-mediated cardiac angiogenesis

Abstract Background Acute myocardial infarction is a major health problem and is the leading cause of death worldwide. Myocardial apoptosis induced by myocardial infarction injury is involved in the pathophysiology of heart failure. Therapeutic stem cell therapy has the potential to be an effective...

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Bibliographic Details
Main Authors: Tingting Wang, Tao Li, Xiaolin Niu, Lang Hu, Jin Cheng, Dong Guo, He Ren, Ran Zhao, Zhaole Ji, Pengyun Liu, Yan Li, Yanjie Guo
Format: Article
Language:English
Published: BMC 2023-02-01
Series:Biology Direct
Subjects:
Myocardial-infarction
Adipose-derived mesenchymal stem cells
Exosomes
miRNA-205
Angiogenesis
Online Access:https://doi.org/10.1186/s13062-023-00361-1

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