Oleic acid-based nanosystems for mitigating acute respiratory distress syndrome in mice through neutrophil suppression: how the particulate size affects therapeutic efficiency

Oleic acid-based nanosystems for mitigating acute respiratory distress syndrome in mice through neutrophil suppression: how the particulate size affects therapeutic efficiency

Abstract Background Oleic acid (OA) is reported to show anti-inflammatory activity toward activated neutrophils. It is also an important material in nanoparticles for increased stability and cellular internalization. We aimed to evaluate the anti-inflammatory activity of injectable OA-based nanopart...

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Bibliographic Details
Main Authors: Huang-Ping Yu, Fu-Chao Liu, Ani Umoro, Zih-Chan Lin, Ahmed O. Elzoghby, Tsong-Long Hwang, Jia-You Fang
Format: Article
Language:English
Published: BMC 2020-01-01
Series:Journal of Nanobiotechnology
Subjects:
Oleic acid
Lipid-based nanoparticles
Size
Anti-inflammation
Neutrophil
Acute respiratory distress syndrome
Online Access:https://doi.org/10.1186/s12951-020-0583-y

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