Oncolytic viral therapies and the delicate balance between virus-macrophage-tumour interactions: A mathematical approach

Oncolytic viral therapies and the delicate balance between virus-macrophage-tumour interactions: A mathematical approach

The success of oncolytic virotherapies depends on the tumour microenvironment, which contains a large number of infiltrating immune cells. In this theoretical study, we derive an ODE model to investigate the interactions between breast cancer tumour cells, an oncolytic virus (Vesicular Stomatitis Vi...

Full description

Bibliographic Details
Main Authors: Nada Almuallem, Dumitru Trucu, Raluca Eftimie
Format: Article
Language:English
Published: AIMS Press 2021-04-01
Series:Mathematical Biosciences and Engineering
Subjects:
mathematical model
vesicular stomatitis virus (vsv)
breast cancer cells
m1 macrophages
m2 macrophages
asymptotic dynamics
Online Access:http://www.aimspress.com/article/doi/10.3934/mbe.2021041?viewType=HTML

Internet

http://www.aimspress.com/article/doi/10.3934/mbe.2021041?viewType=HTML

Similar Items