Genetic Diversity of HLA Class I and Class II Alleles in Thai Populations: Contribution to Genotype-Guided Therapeutics

Genetic Diversity of HLA Class I and Class II Alleles in Thai Populations: Contribution to Genotype-Guided Therapeutics

Human leukocyte antigen (HLA) class I and II are known to have association with severe cutaneous adverse reactions (SCARs) when exposing to certain drug treatment. Due to genetic differences at population level, drug hypersensitivity reactions are varied, and thus common pharmacogenetics markers for...

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Bibliographic Details
Main Authors: Patompong Satapornpong, Pimonpan Jinda, Thawinee Jantararoungtong, Napatrupron Koomdee, Chonlawat Chaichan, Jirawat Pratoomwun, Chalitpon Na Nakorn, Wichai Aekplakorn, Alisa Wilantho, Chumpol Ngamphiw, Sissades Tongsima, Chonlaphat Sukasem
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Pharmacology
Subjects:
human leukocyte antigen
HLA class I
HLA class II
Thai population
pharmacogenetic marker
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.00078/full

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