Rationales, design and recruitment for the Elfe longitudinal study

<p>Abstract</p> <p>Background</p> <p>Many factors act simultaneously in childhood to influence health status, life chances and well being, including pre-birth influences, the environmental pollutants of early life, health status but also the social influences of family...

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Main Authors: Salines Georges, Sarter Hélène, Pirus Claudine, Bois Corinne, Vandentorren Stéphanie, Leridon Henri
Format: Article
Language:English
Published: BMC 2009-09-01
Series:BMC Pediatrics
Online Access:http://www.biomedcentral.com/1471-2431/9/58
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author Salines Georges
Sarter Hélène
Pirus Claudine
Bois Corinne
Vandentorren Stéphanie
Leridon Henri
author_facet Salines Georges
Sarter Hélène
Pirus Claudine
Bois Corinne
Vandentorren Stéphanie
Leridon Henri
author_sort Salines Georges
collection DOAJ
description <p>Abstract</p> <p>Background</p> <p>Many factors act simultaneously in childhood to influence health status, life chances and well being, including pre-birth influences, the environmental pollutants of early life, health status but also the social influences of family and school. A cohort study is needed to disentangle these influences and explore attribution.</p> <p>Methods</p> <p>Elfe will be a nationally representative cohort of 20 000 children followed from birth to adulthood using a multidisciplinary approach. The cohort will be based on the INSEE Permanent Demographic Panel (EDP) established using census data and civil records. The sample size has been defined in order to match the representativeness criteria and to obtain some prevalence estimation, but also to address the research area of low exposure/rare effects. The cohort will be based on repeated surveys by face to face or phone interview (at birth and each year) as well as medical interview (at 2 years) and examination (at 6 years). Furthermore, biological samples will be taken at birth to evaluate the foetal exposition to toxic substances, environmental sensors will be placed in the child's homes. Pilot studies have been initiated in 2007 (500 children) with an overall acceptance rate of 55% and are currently under progress, the 2-year survey being carried out in October this year.</p> <p>Discussion</p> <p>The longitudinal study will provide a unique source of data to analyse the development of children in their environment, to study the various factors interacting throughout the life course up to adulthood and to determine the impact of childhood experience on the individual's physical, psychological, social and professional development.</p>
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spelling doaj.art-7a84a328020b4f24950cfd4a2ae393be2022-12-21T23:36:59ZengBMCBMC Pediatrics1471-24312009-09-01915810.1186/1471-2431-9-58Rationales, design and recruitment for the Elfe longitudinal studySalines GeorgesSarter HélènePirus ClaudineBois CorinneVandentorren StéphanieLeridon Henri<p>Abstract</p> <p>Background</p> <p>Many factors act simultaneously in childhood to influence health status, life chances and well being, including pre-birth influences, the environmental pollutants of early life, health status but also the social influences of family and school. A cohort study is needed to disentangle these influences and explore attribution.</p> <p>Methods</p> <p>Elfe will be a nationally representative cohort of 20 000 children followed from birth to adulthood using a multidisciplinary approach. The cohort will be based on the INSEE Permanent Demographic Panel (EDP) established using census data and civil records. The sample size has been defined in order to match the representativeness criteria and to obtain some prevalence estimation, but also to address the research area of low exposure/rare effects. The cohort will be based on repeated surveys by face to face or phone interview (at birth and each year) as well as medical interview (at 2 years) and examination (at 6 years). Furthermore, biological samples will be taken at birth to evaluate the foetal exposition to toxic substances, environmental sensors will be placed in the child's homes. Pilot studies have been initiated in 2007 (500 children) with an overall acceptance rate of 55% and are currently under progress, the 2-year survey being carried out in October this year.</p> <p>Discussion</p> <p>The longitudinal study will provide a unique source of data to analyse the development of children in their environment, to study the various factors interacting throughout the life course up to adulthood and to determine the impact of childhood experience on the individual's physical, psychological, social and professional development.</p>http://www.biomedcentral.com/1471-2431/9/58
spellingShingle Salines Georges
Sarter Hélène
Pirus Claudine
Bois Corinne
Vandentorren Stéphanie
Leridon Henri
Rationales, design and recruitment for the Elfe longitudinal study
BMC Pediatrics
title Rationales, design and recruitment for the Elfe longitudinal study
title_full Rationales, design and recruitment for the Elfe longitudinal study
title_fullStr Rationales, design and recruitment for the Elfe longitudinal study
title_full_unstemmed Rationales, design and recruitment for the Elfe longitudinal study
title_short Rationales, design and recruitment for the Elfe longitudinal study
title_sort rationales design and recruitment for the elfe longitudinal study
url http://www.biomedcentral.com/1471-2431/9/58
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AT sarterhelene rationalesdesignandrecruitmentfortheelfelongitudinalstudy
AT pirusclaudine rationalesdesignandrecruitmentfortheelfelongitudinalstudy
AT boiscorinne rationalesdesignandrecruitmentfortheelfelongitudinalstudy
AT vandentorrenstephanie rationalesdesignandrecruitmentfortheelfelongitudinalstudy
AT leridonhenri rationalesdesignandrecruitmentfortheelfelongitudinalstudy