Anti-Inflammatory, Antidiabetic Properties and In Silico Modeling of Cucurbitane-Type Triterpene Glycosides from Fruits of an Indian Cultivar of <i>Momordica charantia</i> L.
Diabetes mellitus is a chronic disease and one of the fastest-growing health challenges of the last decades. Studies have shown that chronic low-grade inflammation and activation of the innate immune system are intimately involved in type 2 diabetes pathogenesis. <i>Momordica charantia</i&g...
Main Authors: | Wilmer H. Perera, Siddanagouda R. Shivanagoudra, Jose L. Pérez, Da Mi Kim, Yuxiang Sun, Guddadarangavvanahally K. Jayaprakasha, Bhimanagouda S. Patil |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-02-01
|
Series: | Molecules |
Subjects: | |
Online Access: | https://www.mdpi.com/1420-3049/26/4/1038 |
Similar Items
-
Cucurbitane-Type Triterpene Glycosides from Momordica charantia and Their α-Glucosidase Inhibitory Activities
by: Ya Gao, et al.
Published: (2020-05-01) -
Cucurbitane-type glycosides from the fruits of Momordica charantia and their hypoglycaemic and cytotoxic activities
by: Li-Jie Zhang, et al.
Published: (2014-01-01) -
Four cucurbitane glycosides taimordisins A–D with novel furopyranone skeletons isolated from the fruits of Momordica charantia
by: Chia-Ching Liaw, et al.
Published: (2022-06-01) -
Cucurbitane triterpenoids from Momordica charantia L. and their inhibitory activity against α-glucosidase, α-amylase and protein tyrosine phosphatase 1B (PTP1B)
by: Jiayin Yue, et al.
Published: (2017-10-01) -
Bitter melon extracts and cucurbitane-type triterpenoid glycosides antagonize lipopolysaccharide-induced inflammation via suppression of NLRP3 inflammasome
by: Jose L. Perez, et al.
Published: (2021-11-01)