Versatile generation of precise gene edits in bovines using SEGCPN

Versatile generation of precise gene edits in bovines using SEGCPN

Abstract Background Gene knockout and knock-in have been widely performed in large farm animals based on genome editing systems. However, many types of precise gene editing, including targeted deletion, gene tagging, and large gene fragment replacement, remain a challenge in large farm animals. Resu...

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Bibliographic Details
Main Authors: Ming Wang, Fangrong Ding, Haiping Wang, Ling Li, Yunping Dai, ZhaoLin Sun, Ning Li
Format: Article
Language:English
Published: BMC 2023-10-01
Series:BMC Biology
Subjects:
Bovine
Precise gene editing
Point mutation
Targeted deletion
Gene tagging
Gene replacement
Online Access:https://doi.org/10.1186/s12915-023-01677-0

Internet

https://doi.org/10.1186/s12915-023-01677-0

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