Nutraceuticals for Complementary Treatment of Multisystem Inflammatory Syndrome in Children: A Perspective from Their Use in COVID-19
Multisystem inflammatory syndrome in children (MIS-C) has been widely reported in some children diagnosed with SARS-CoV-2. Clinical signs of MIS-C are manifested at 2 to 4 weeks after SARS-CoV-2 infection, where elevated biomarkers of inflammation and cardiac dysfunction are the hallmark of this syn...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-10-01
|
| Series: | Life |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2075-1729/12/10/1652 |
| _version_ | 1797471935309807616 |
|---|---|
| author | Diego Estrada-Luna Elizabeth Carreón-Torres Susana González-Reyes María Fernanda Martínez-Salazar María Araceli Ortiz-Rodríguez Esther Ramírez-Moreno José Arias-Rico Angélica Saraí Jiménez-Osorio |
| author_facet | Diego Estrada-Luna Elizabeth Carreón-Torres Susana González-Reyes María Fernanda Martínez-Salazar María Araceli Ortiz-Rodríguez Esther Ramírez-Moreno José Arias-Rico Angélica Saraí Jiménez-Osorio |
| author_sort | Diego Estrada-Luna |
| collection | DOAJ |
| description | Multisystem inflammatory syndrome in children (MIS-C) has been widely reported in some children diagnosed with SARS-CoV-2. Clinical signs of MIS-C are manifested at 2 to 4 weeks after SARS-CoV-2 infection, where elevated biomarkers of inflammation and cardiac dysfunction are the hallmark of this syndrome when infection or exposure to SARS-CoV-2 has been confirmed. However, after two years of acknowledgment, MIS-C treatment is still under research to reach safety and effectiveness in the acute phase in children. Therefore, in this review, we discuss the potential use of natural compounds with antioxidant and anti-inflammatory effects to reduce collateral damage caused by hyperinflammation in MIS-C pathology for new research in treatment and interventions. |
| first_indexed | 2024-03-09T19:56:00Z |
| format | Article |
| id | doaj.art-7a8dbd1be4f84405b46df7e02519a2ba |
| institution | Directory Open Access Journal |
| issn | 2075-1729 |
| language | English |
| last_indexed | 2024-03-09T19:56:00Z |
| publishDate | 2022-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Life |
| spelling | doaj.art-7a8dbd1be4f84405b46df7e02519a2ba2023-11-24T00:57:56ZengMDPI AGLife2075-17292022-10-011210165210.3390/life12101652Nutraceuticals for Complementary Treatment of Multisystem Inflammatory Syndrome in Children: A Perspective from Their Use in COVID-19Diego Estrada-Luna0Elizabeth Carreón-Torres1Susana González-Reyes2María Fernanda Martínez-Salazar3María Araceli Ortiz-Rodríguez4Esther Ramírez-Moreno5José Arias-Rico6Angélica Saraí Jiménez-Osorio7Área Académica de Enfermería, Instituto de Ciencias de la Salud, Universidad Autónoma del Estado Hidalgo, Circuito Ex Hacienda La Concepción S/N, Carretera Pachuca-Actopan, San Agustín Tlaxiaca 42160, MexicoDepartment of Molecular Biology, Instituto Nacional de Cardiología Ignacio Chávez, Juan Badiano 1, Sección XVI, Tlalpan, Mexico City 14080, MexicoFacultad de Medicina y Psicología, Universidad Autónoma de Baja California, Tijuana 22390, MexicoFacultad de Ciencias del Deporte, Universidad Autónoma del Estado de Morelos, Av. Universidad No. 1001 Col. Chamilpa, Cuernavaca 62209, MexicoFacultad de Nutrición, Universidad Autónoma del Estado de Morelos, Iztaccíhuatl 100 Col. Los Volcanes, Cuernavaca 62350, MexicoÁrea Académica de Nutrición, Instituto de Ciencias de la Salud, Universidad Autónoma del Estado Hidalgo, Circuito Ex Hacienda La Concepción S/N, Carretera Pachuca-Actopan, San Agustín Tlaxiaca 42160, MexicoÁrea Académica de Enfermería, Instituto de Ciencias de la Salud, Universidad Autónoma del Estado Hidalgo, Circuito Ex Hacienda La Concepción S/N, Carretera Pachuca-Actopan, San Agustín Tlaxiaca 42160, MexicoÁrea Académica de Enfermería, Instituto de Ciencias de la Salud, Universidad Autónoma del Estado Hidalgo, Circuito Ex Hacienda La Concepción S/N, Carretera Pachuca-Actopan, San Agustín Tlaxiaca 42160, MexicoMultisystem inflammatory syndrome in children (MIS-C) has been widely reported in some children diagnosed with SARS-CoV-2. Clinical signs of MIS-C are manifested at 2 to 4 weeks after SARS-CoV-2 infection, where elevated biomarkers of inflammation and cardiac dysfunction are the hallmark of this syndrome when infection or exposure to SARS-CoV-2 has been confirmed. However, after two years of acknowledgment, MIS-C treatment is still under research to reach safety and effectiveness in the acute phase in children. Therefore, in this review, we discuss the potential use of natural compounds with antioxidant and anti-inflammatory effects to reduce collateral damage caused by hyperinflammation in MIS-C pathology for new research in treatment and interventions.https://www.mdpi.com/2075-1729/12/10/1652multisystem inflammatory syndromechildrennutraceutical compounds |
| spellingShingle | Diego Estrada-Luna Elizabeth Carreón-Torres Susana González-Reyes María Fernanda Martínez-Salazar María Araceli Ortiz-Rodríguez Esther Ramírez-Moreno José Arias-Rico Angélica Saraí Jiménez-Osorio Nutraceuticals for Complementary Treatment of Multisystem Inflammatory Syndrome in Children: A Perspective from Their Use in COVID-19 Life multisystem inflammatory syndrome children nutraceutical compounds |
| title | Nutraceuticals for Complementary Treatment of Multisystem Inflammatory Syndrome in Children: A Perspective from Their Use in COVID-19 |
| title_full | Nutraceuticals for Complementary Treatment of Multisystem Inflammatory Syndrome in Children: A Perspective from Their Use in COVID-19 |
| title_fullStr | Nutraceuticals for Complementary Treatment of Multisystem Inflammatory Syndrome in Children: A Perspective from Their Use in COVID-19 |
| title_full_unstemmed | Nutraceuticals for Complementary Treatment of Multisystem Inflammatory Syndrome in Children: A Perspective from Their Use in COVID-19 |
| title_short | Nutraceuticals for Complementary Treatment of Multisystem Inflammatory Syndrome in Children: A Perspective from Their Use in COVID-19 |
| title_sort | nutraceuticals for complementary treatment of multisystem inflammatory syndrome in children a perspective from their use in covid 19 |
| topic | multisystem inflammatory syndrome children nutraceutical compounds |
| url | https://www.mdpi.com/2075-1729/12/10/1652 |
| work_keys_str_mv | AT diegoestradaluna nutraceuticalsforcomplementarytreatmentofmultisysteminflammatorysyndromeinchildrenaperspectivefromtheiruseincovid19 AT elizabethcarreontorres nutraceuticalsforcomplementarytreatmentofmultisysteminflammatorysyndromeinchildrenaperspectivefromtheiruseincovid19 AT susanagonzalezreyes nutraceuticalsforcomplementarytreatmentofmultisysteminflammatorysyndromeinchildrenaperspectivefromtheiruseincovid19 AT mariafernandamartinezsalazar nutraceuticalsforcomplementarytreatmentofmultisysteminflammatorysyndromeinchildrenaperspectivefromtheiruseincovid19 AT mariaaraceliortizrodriguez nutraceuticalsforcomplementarytreatmentofmultisysteminflammatorysyndromeinchildrenaperspectivefromtheiruseincovid19 AT estherramirezmoreno nutraceuticalsforcomplementarytreatmentofmultisysteminflammatorysyndromeinchildrenaperspectivefromtheiruseincovid19 AT joseariasrico nutraceuticalsforcomplementarytreatmentofmultisysteminflammatorysyndromeinchildrenaperspectivefromtheiruseincovid19 AT angelicasaraijimenezosorio nutraceuticalsforcomplementarytreatmentofmultisysteminflammatorysyndromeinchildrenaperspectivefromtheiruseincovid19 |