Fetal Middle Cerebral Artery Pulsatility Index in No-Risk Pregnancies: Effects of Auditory Stimulation and Pregnancy Order
Pulsatility index (PI) values in a fetal middle cerebral artery (MCA) were compared in no-risk pregnancies to examine the differences related to auditory stimulation test and pregnancy order. The study included 196 women with no-risk pregnancies selected from the database of more than 1000 pregnant...
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| Format: | Article |
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MDPI AG
2020-05-01
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| Series: | International Journal of Molecular Sciences |
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| Online Access: | https://www.mdpi.com/1422-0067/21/11/3855 |
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| author | Ljiljana Jeličić Svetlana Janković Mirjana Sovilj Tatjana Adamović Ivana Bogavac Aleksandar Gavrilović Miško Subotić |
| author_facet | Ljiljana Jeličić Svetlana Janković Mirjana Sovilj Tatjana Adamović Ivana Bogavac Aleksandar Gavrilović Miško Subotić |
| author_sort | Ljiljana Jeličić |
| collection | DOAJ |
| description | Pulsatility index (PI) values in a fetal middle cerebral artery (MCA) were compared in no-risk pregnancies to examine the differences related to auditory stimulation test and pregnancy order. The study included 196 women with no-risk pregnancies selected from the database of more than 1000 pregnant women divided into two groups. Group 1 consisted of 98 nulliparous women (C1 = 98) and Group 2 consisted of 98 parous women (C2 = 98). All pregnant women were of comparable age and fetal gestational age (GA) when MCA-PI values were recorded. Measurements of PI values in fetal MCA were obtained before and immediately after the application of fetal auditory stimulation test. The MCA-PI measuring was conducted in the period between the 36th and the 41st week of GA. The results showed that PI baseline values and PI values after defined auditory stimulation were significantly different when measured in nulliparous women compared to parous women (<i>p</i> = 0.001; <i>p</i> = 0.003, respectively), while no group differences were observed in relative PI value changes due to auditory stimulation. These findings suggest that hemodynamic changes in fetal MCA caused by defined auditory stimulation measured by PI value changes may be valuable in the assessment of fetal auditory perception functionality and its development. |
| first_indexed | 2024-03-10T19:31:37Z |
| format | Article |
| id | doaj.art-7a900956aedc4a159764893c156cece2 |
| institution | Directory Open Access Journal |
| issn | 1661-6596 1422-0067 |
| language | English |
| last_indexed | 2024-03-10T19:31:37Z |
| publishDate | 2020-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | International Journal of Molecular Sciences |
| spelling | doaj.art-7a900956aedc4a159764893c156cece22023-11-20T02:06:38ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672020-05-012111385510.3390/ijms21113855Fetal Middle Cerebral Artery Pulsatility Index in No-Risk Pregnancies: Effects of Auditory Stimulation and Pregnancy OrderLjiljana Jeličić0Svetlana Janković1Mirjana Sovilj2Tatjana Adamović3Ivana Bogavac4Aleksandar Gavrilović5Miško Subotić6Cognitive Neuroscience Department Research and Development Institute “Life Activities Advancement Center”, Belgrade 11000, SerbiaDepartment of Acute Perinatal Pathology, Belgrade University Medical School, Belgrade 11000, SerbiaDepartment of Speech, Language and Hearing Sciences, Institute for Experimental Phonetics and Speech Pathology, Belgrade 11000, SerbiaCognitive Neuroscience Department Research and Development Institute “Life Activities Advancement Center”, Belgrade 11000, SerbiaCognitive Neuroscience Department Research and Development Institute “Life Activities Advancement Center”, Belgrade 11000, SerbiaDepartment of Neurology, Faculty of Medical Sciences, University of Kragujevac, Kragujevac 34000, SerbiaCognitive Neuroscience Department Research and Development Institute “Life Activities Advancement Center”, Belgrade 11000, SerbiaPulsatility index (PI) values in a fetal middle cerebral artery (MCA) were compared in no-risk pregnancies to examine the differences related to auditory stimulation test and pregnancy order. The study included 196 women with no-risk pregnancies selected from the database of more than 1000 pregnant women divided into two groups. Group 1 consisted of 98 nulliparous women (C1 = 98) and Group 2 consisted of 98 parous women (C2 = 98). All pregnant women were of comparable age and fetal gestational age (GA) when MCA-PI values were recorded. Measurements of PI values in fetal MCA were obtained before and immediately after the application of fetal auditory stimulation test. The MCA-PI measuring was conducted in the period between the 36th and the 41st week of GA. The results showed that PI baseline values and PI values after defined auditory stimulation were significantly different when measured in nulliparous women compared to parous women (<i>p</i> = 0.001; <i>p</i> = 0.003, respectively), while no group differences were observed in relative PI value changes due to auditory stimulation. These findings suggest that hemodynamic changes in fetal MCA caused by defined auditory stimulation measured by PI value changes may be valuable in the assessment of fetal auditory perception functionality and its development.https://www.mdpi.com/1422-0067/21/11/3855Pulsatility indexfetal auditory perceptionparous and nulliparous pregnancymiddle cerebral artery |
| spellingShingle | Ljiljana Jeličić Svetlana Janković Mirjana Sovilj Tatjana Adamović Ivana Bogavac Aleksandar Gavrilović Miško Subotić Fetal Middle Cerebral Artery Pulsatility Index in No-Risk Pregnancies: Effects of Auditory Stimulation and Pregnancy Order International Journal of Molecular Sciences Pulsatility index fetal auditory perception parous and nulliparous pregnancy middle cerebral artery |
| title | Fetal Middle Cerebral Artery Pulsatility Index in No-Risk Pregnancies: Effects of Auditory Stimulation and Pregnancy Order |
| title_full | Fetal Middle Cerebral Artery Pulsatility Index in No-Risk Pregnancies: Effects of Auditory Stimulation and Pregnancy Order |
| title_fullStr | Fetal Middle Cerebral Artery Pulsatility Index in No-Risk Pregnancies: Effects of Auditory Stimulation and Pregnancy Order |
| title_full_unstemmed | Fetal Middle Cerebral Artery Pulsatility Index in No-Risk Pregnancies: Effects of Auditory Stimulation and Pregnancy Order |
| title_short | Fetal Middle Cerebral Artery Pulsatility Index in No-Risk Pregnancies: Effects of Auditory Stimulation and Pregnancy Order |
| title_sort | fetal middle cerebral artery pulsatility index in no risk pregnancies effects of auditory stimulation and pregnancy order |
| topic | Pulsatility index fetal auditory perception parous and nulliparous pregnancy middle cerebral artery |
| url | https://www.mdpi.com/1422-0067/21/11/3855 |
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