Pyoderma gangrenosum as a initial manifestation of ulcerative proctocolitis
pyoderma gangrenosum is a rare inflammatory skin condition characterized by progressive and recurrent skin ulceration of destructive course. It is usually associated with rheumatoid arthritis, paraproteinemia, myeloproliferative diseases and inflammatory bowel diseases, especially non-specific ulcer...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Thieme Revinter Publicações Ltda.
2011-09-01
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| Series: | Journal of Coloproctology |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2237-93632011000300013 |
| _version_ | 1818438622667341824 |
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| author | Carla Bortolin Fonseca Guilherme Lang Motta Alexandre Rampazzo João Carlos Cantarelli Junior Renato Borges Fagundes |
| author_facet | Carla Bortolin Fonseca Guilherme Lang Motta Alexandre Rampazzo João Carlos Cantarelli Junior Renato Borges Fagundes |
| author_sort | Carla Bortolin Fonseca |
| collection | DOAJ |
| description | pyoderma gangrenosum is a rare inflammatory skin condition characterized by progressive and recurrent skin ulceration of destructive course. It is usually associated with rheumatoid arthritis, paraproteinemia, myeloproliferative diseases and inflammatory bowel diseases, especially non-specific ulcerative proctocolitis. In these situations, skin lesions are described as concurrent with the intestinal condition. However, reports on pyoderma gangrenosum preceding intestinal findings are less frequent. The authors describe a case of a woman with febrile condition associated with skin lesions diagnosed by biopsy as pyoderma gangrenosum. Two weeks later, she developed diarrhea, arthralgia and sepsis, being diagnosed as ulcerative proctocolitis. After the administration of the treatment for ulcerative proctocolitis, she showed improvements in sepsis care, remission of diarrhea and regression of skin lesions. This case highlights the importance of considering pyoderma gangrenosum as a manifestation associated with inflammatory bowel disease, regardless of its timing in relation to intestinal symptoms.<br>Pioderma gangrenoso é uma forma de inflamação cutânea, caracterizada por ulceração progressiva e recorrente da pele, com curso destrutivo. Geralmente é associada à artrite reumatoide, paraproteinemia, doenças mieloproliferativas e doença inflamatória intestinal, em especial retocolite ulcerativa inespecífica. Em tais casos, as lesões cutâneas são descritas concomitantes ao quadro intestinal, porém, relatos com descrição de pioderma gangrenoso precedendo achados intestinais são menos frequentes. Os autores relatam caso de mulher com quadro febril associado a lesões cutâneas diagnosticadas por biópsia como pioderma gangrenoso. Duas semanas depois, apresentou diarreia, artralgia e sepse sendo diagnosticada retocolite ulcerativa. Com o tratamento para retocolite ulcerativa apresentou melhora do quadro séptico, remissão da diarreia e regressão das lesões cutâneas. Este caso enfatiza a importância em considerar o pioderma gangrenoso como manifestação associada à doença inflamatória intestinal, independente de sua temporalidade em relação aos sintomas intestinais. |
| first_indexed | 2024-12-14T17:43:30Z |
| format | Article |
| id | doaj.art-7a909c22a22248d584f9311cbaa75ca6 |
| institution | Directory Open Access Journal |
| issn | 2237-9363 |
| language | English |
| last_indexed | 2024-12-14T17:43:30Z |
| publishDate | 2011-09-01 |
| publisher | Thieme Revinter Publicações Ltda. |
| record_format | Article |
| series | Journal of Coloproctology |
| spelling | doaj.art-7a909c22a22248d584f9311cbaa75ca62022-12-21T22:52:47ZengThieme Revinter Publicações Ltda.Journal of Coloproctology2237-93632011-09-0131330130510.1590/S2237-93632011000300013Pyoderma gangrenosum as a initial manifestation of ulcerative proctocolitisCarla Bortolin FonsecaGuilherme Lang MottaAlexandre RampazzoJoão Carlos Cantarelli JuniorRenato Borges Fagundespyoderma gangrenosum is a rare inflammatory skin condition characterized by progressive and recurrent skin ulceration of destructive course. It is usually associated with rheumatoid arthritis, paraproteinemia, myeloproliferative diseases and inflammatory bowel diseases, especially non-specific ulcerative proctocolitis. In these situations, skin lesions are described as concurrent with the intestinal condition. However, reports on pyoderma gangrenosum preceding intestinal findings are less frequent. The authors describe a case of a woman with febrile condition associated with skin lesions diagnosed by biopsy as pyoderma gangrenosum. Two weeks later, she developed diarrhea, arthralgia and sepsis, being diagnosed as ulcerative proctocolitis. After the administration of the treatment for ulcerative proctocolitis, she showed improvements in sepsis care, remission of diarrhea and regression of skin lesions. This case highlights the importance of considering pyoderma gangrenosum as a manifestation associated with inflammatory bowel disease, regardless of its timing in relation to intestinal symptoms.<br>Pioderma gangrenoso é uma forma de inflamação cutânea, caracterizada por ulceração progressiva e recorrente da pele, com curso destrutivo. Geralmente é associada à artrite reumatoide, paraproteinemia, doenças mieloproliferativas e doença inflamatória intestinal, em especial retocolite ulcerativa inespecífica. Em tais casos, as lesões cutâneas são descritas concomitantes ao quadro intestinal, porém, relatos com descrição de pioderma gangrenoso precedendo achados intestinais são menos frequentes. Os autores relatam caso de mulher com quadro febril associado a lesões cutâneas diagnosticadas por biópsia como pioderma gangrenoso. Duas semanas depois, apresentou diarreia, artralgia e sepse sendo diagnosticada retocolite ulcerativa. Com o tratamento para retocolite ulcerativa apresentou melhora do quadro séptico, remissão da diarreia e regressão das lesões cutâneas. Este caso enfatiza a importância em considerar o pioderma gangrenoso como manifestação associada à doença inflamatória intestinal, independente de sua temporalidade em relação aos sintomas intestinais.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2237-93632011000300013pioderma gangrenosoproctocolitepiodermacolitepyoderma gangrenosumproctocolitispyodermacolitis |
| spellingShingle | Carla Bortolin Fonseca Guilherme Lang Motta Alexandre Rampazzo João Carlos Cantarelli Junior Renato Borges Fagundes Pyoderma gangrenosum as a initial manifestation of ulcerative proctocolitis Journal of Coloproctology pioderma gangrenoso proctocolite pioderma colite pyoderma gangrenosum proctocolitis pyoderma colitis |
| title | Pyoderma gangrenosum as a initial manifestation of ulcerative proctocolitis |
| title_full | Pyoderma gangrenosum as a initial manifestation of ulcerative proctocolitis |
| title_fullStr | Pyoderma gangrenosum as a initial manifestation of ulcerative proctocolitis |
| title_full_unstemmed | Pyoderma gangrenosum as a initial manifestation of ulcerative proctocolitis |
| title_short | Pyoderma gangrenosum as a initial manifestation of ulcerative proctocolitis |
| title_sort | pyoderma gangrenosum as a initial manifestation of ulcerative proctocolitis |
| topic | pioderma gangrenoso proctocolite pioderma colite pyoderma gangrenosum proctocolitis pyoderma colitis |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2237-93632011000300013 |
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