Molecular Targeting of Acid Ceramidase in Glioblastoma: A Review of Its Role, Potential Treatment, and Challenges
Glioblastoma is the most common, malignant primary tumor of the central nervous system. The average prognosis for life expectancy after diagnosis, with the triad of surgery, chemotherapy, and radiation therapy, is less than 1.5 years. Chemotherapy treatment is mostly limited to temozolomide. In this...
Main Authors: | Ha S. Nguyen, Ahmed J. Awad, Saman Shabani, Ninh Doan |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2018-04-01
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Series: | Pharmaceutics |
Subjects: | |
Online Access: | http://www.mdpi.com/1999-4923/10/2/45 |
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