Prevalence of oral lesions in kidney transplant patients: A single center experience

Kidney transplant patients (KTPs) have a potential tendency to develop oral lesions due to the administration of immunosuppressive drugs, but their prevalence is still obscure. The aim of the present study was to investigate the oral clinical findings in a group of renal transplant patients in compa...

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Main Authors: Sumita Kaswan, Santosh Patil, Sneha Maheshwari, Richa Wadhawan
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2015-01-01
Series:Saudi Journal of Kidney Diseases and Transplantation
Online Access:http://www.sjkdt.org/article.asp?issn=1319-2442;year=2015;volume=26;issue=4;spage=678;epage=683;aulast=Kaswan
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author Sumita Kaswan
Santosh Patil
Sneha Maheshwari
Richa Wadhawan
author_facet Sumita Kaswan
Santosh Patil
Sneha Maheshwari
Richa Wadhawan
author_sort Sumita Kaswan
collection DOAJ
description Kidney transplant patients (KTPs) have a potential tendency to develop oral lesions due to the administration of immunosuppressive drugs, but their prevalence is still obscure. The aim of the present study was to investigate the oral clinical findings in a group of renal transplant patients in comparison with ageand sex-matched healthy controls (HCs). Three hundred KTPs who underwent transplantation at least six months earlier and 296 HCs were examined clinically for the presence of any oral lesions. Demographic and additional details regarding medications, systemic diseases and duration after transplantation were recorded. Statistical analysis was performed using the Chi-square test, with significance set at P <0.05. The prevalence of oral lesions in KTPs was 56.8% as compared with 29.7% in HCs. The most common lesion observed in KTPs was gingival overgrowth (21.8%), followed by candidiasis (17.1%). Coated tongue (15.9%), followed by leukoplakia (11.3%), were common in HCs. Both gingival hyperplasia and coated tongue were significantly related to poor oral hygiene (P <0.05), but were not significantly related to the immunosuppressive therapy (P >0.05). The findings of the present study indicate the need for a routine and regular oral health check-up, with emphasis on maintenance of oral hygiene for renal transplant patients.
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spelling doaj.art-7a9340078d82489f8d6ee09567d1bd152022-12-22T02:19:05ZengWolters Kluwer Medknow PublicationsSaudi Journal of Kidney Diseases and Transplantation1319-24422015-01-0126467868310.4103/1319-2442.160128Prevalence of oral lesions in kidney transplant patients: A single center experienceSumita KaswanSantosh PatilSneha MaheshwariRicha WadhawanKidney transplant patients (KTPs) have a potential tendency to develop oral lesions due to the administration of immunosuppressive drugs, but their prevalence is still obscure. The aim of the present study was to investigate the oral clinical findings in a group of renal transplant patients in comparison with ageand sex-matched healthy controls (HCs). Three hundred KTPs who underwent transplantation at least six months earlier and 296 HCs were examined clinically for the presence of any oral lesions. Demographic and additional details regarding medications, systemic diseases and duration after transplantation were recorded. Statistical analysis was performed using the Chi-square test, with significance set at P <0.05. The prevalence of oral lesions in KTPs was 56.8% as compared with 29.7% in HCs. The most common lesion observed in KTPs was gingival overgrowth (21.8%), followed by candidiasis (17.1%). Coated tongue (15.9%), followed by leukoplakia (11.3%), were common in HCs. Both gingival hyperplasia and coated tongue were significantly related to poor oral hygiene (P <0.05), but were not significantly related to the immunosuppressive therapy (P >0.05). The findings of the present study indicate the need for a routine and regular oral health check-up, with emphasis on maintenance of oral hygiene for renal transplant patients.http://www.sjkdt.org/article.asp?issn=1319-2442;year=2015;volume=26;issue=4;spage=678;epage=683;aulast=Kaswan
spellingShingle Sumita Kaswan
Santosh Patil
Sneha Maheshwari
Richa Wadhawan
Prevalence of oral lesions in kidney transplant patients: A single center experience
Saudi Journal of Kidney Diseases and Transplantation
title Prevalence of oral lesions in kidney transplant patients: A single center experience
title_full Prevalence of oral lesions in kidney transplant patients: A single center experience
title_fullStr Prevalence of oral lesions in kidney transplant patients: A single center experience
title_full_unstemmed Prevalence of oral lesions in kidney transplant patients: A single center experience
title_short Prevalence of oral lesions in kidney transplant patients: A single center experience
title_sort prevalence of oral lesions in kidney transplant patients a single center experience
url http://www.sjkdt.org/article.asp?issn=1319-2442;year=2015;volume=26;issue=4;spage=678;epage=683;aulast=Kaswan
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AT richawadhawan prevalenceoforallesionsinkidneytransplantpatientsasinglecenterexperience