Distinct Features of Germinal Center Reactions in Macaques Infected by SIV or Vaccinated with a T-Dependent Model Antigen

Distinct Features of Germinal Center Reactions in Macaques Infected by SIV or Vaccinated with a T-Dependent Model Antigen

B-cell follicles constitute large reservoirs of infectious HIV/SIV associated to follicular dendritic cells and infecting follicular helper (T<sub>FH</sub>) and regulatory (T<sub>FR</sub>) T-cells in germinal centers (GCs). Thus, follicular and GC B-cells are persistently exp...

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Bibliographic Details
Main Authors: Maria Trovato, Hany M. Ibrahim, Stephane Isnard, Roger Le Grand, Nathalie Bosquet, Gwenoline Borhis, Yolande Richard
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Viruses
Subjects:
B-cells
SIV
GC
T<sub>FH</sub>
CXCL10
CXCL13
Online Access:https://www.mdpi.com/1999-4915/13/2/263

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