Advanced Strategies for Tissue Engineering in Regenerative Medicine: A Biofabrication and Biopolymer Perspective

Tissue engineering is known to encompass multiple aspects of science, medicine and engineering. The development of systems which are able to promote the growth of new cells and tissue components are vital in the treatment of severe tissue injury and damage. This can be done through a variety of diff...

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Main Authors: Courtney R. Lynch, Pierre P. D. Kondiah, Yahya E. Choonara
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/26/9/2518
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author Courtney R. Lynch
Pierre P. D. Kondiah
Yahya E. Choonara
author_facet Courtney R. Lynch
Pierre P. D. Kondiah
Yahya E. Choonara
author_sort Courtney R. Lynch
collection DOAJ
description Tissue engineering is known to encompass multiple aspects of science, medicine and engineering. The development of systems which are able to promote the growth of new cells and tissue components are vital in the treatment of severe tissue injury and damage. This can be done through a variety of different biofabrication strategies including the use of hydrogels, 3D bioprinted scaffolds and nanotechnology. The incorporation of stem cells into these systems and the advantage of this is also discussed. Biopolymers, those which have a natural original, have been particularly advantageous in tissue engineering systems as they are often found within the extracellular matrix of the human body. The utilization of biopolymers has become increasing popular as they are biocompatible, biodegradable and do not illicit an immune response when placed into the body. Tissue engineering systems for use with the eye are also discussed. This is of particular interest as the eye is known as an immune privileged site resulting in an extremely limited ability for natural cell regeneration.
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spelling doaj.art-7a93c9000a714d09b728bd3e3619801a2023-11-21T17:11:23ZengMDPI AGMolecules1420-30492021-04-01269251810.3390/molecules26092518Advanced Strategies for Tissue Engineering in Regenerative Medicine: A Biofabrication and Biopolymer PerspectiveCourtney R. Lynch0Pierre P. D. Kondiah1Yahya E. Choonara2Wits Advanced Drug Delivery Platform Research Unit, Department of Pharmacy and Pharmacology, School of Therapeutic Sciences, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, 7 York Road, Parktown 2193, South AfricaWits Advanced Drug Delivery Platform Research Unit, Department of Pharmacy and Pharmacology, School of Therapeutic Sciences, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, 7 York Road, Parktown 2193, South AfricaWits Advanced Drug Delivery Platform Research Unit, Department of Pharmacy and Pharmacology, School of Therapeutic Sciences, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, 7 York Road, Parktown 2193, South AfricaTissue engineering is known to encompass multiple aspects of science, medicine and engineering. The development of systems which are able to promote the growth of new cells and tissue components are vital in the treatment of severe tissue injury and damage. This can be done through a variety of different biofabrication strategies including the use of hydrogels, 3D bioprinted scaffolds and nanotechnology. The incorporation of stem cells into these systems and the advantage of this is also discussed. Biopolymers, those which have a natural original, have been particularly advantageous in tissue engineering systems as they are often found within the extracellular matrix of the human body. The utilization of biopolymers has become increasing popular as they are biocompatible, biodegradable and do not illicit an immune response when placed into the body. Tissue engineering systems for use with the eye are also discussed. This is of particular interest as the eye is known as an immune privileged site resulting in an extremely limited ability for natural cell regeneration.https://www.mdpi.com/1420-3049/26/9/2518tissue engineeringbiomaterialsnatural polymerscell regeneration
spellingShingle Courtney R. Lynch
Pierre P. D. Kondiah
Yahya E. Choonara
Advanced Strategies for Tissue Engineering in Regenerative Medicine: A Biofabrication and Biopolymer Perspective
Molecules
tissue engineering
biomaterials
natural polymers
cell regeneration
title Advanced Strategies for Tissue Engineering in Regenerative Medicine: A Biofabrication and Biopolymer Perspective
title_full Advanced Strategies for Tissue Engineering in Regenerative Medicine: A Biofabrication and Biopolymer Perspective
title_fullStr Advanced Strategies for Tissue Engineering in Regenerative Medicine: A Biofabrication and Biopolymer Perspective
title_full_unstemmed Advanced Strategies for Tissue Engineering in Regenerative Medicine: A Biofabrication and Biopolymer Perspective
title_short Advanced Strategies for Tissue Engineering in Regenerative Medicine: A Biofabrication and Biopolymer Perspective
title_sort advanced strategies for tissue engineering in regenerative medicine a biofabrication and biopolymer perspective
topic tissue engineering
biomaterials
natural polymers
cell regeneration
url https://www.mdpi.com/1420-3049/26/9/2518
work_keys_str_mv AT courtneyrlynch advancedstrategiesfortissueengineeringinregenerativemedicineabiofabricationandbiopolymerperspective
AT pierrepdkondiah advancedstrategiesfortissueengineeringinregenerativemedicineabiofabricationandbiopolymerperspective
AT yahyaechoonara advancedstrategiesfortissueengineeringinregenerativemedicineabiofabricationandbiopolymerperspective