Association between education and the risk of incident coronary heart disease among middle-aged and older Chinese: the Dongfeng-Tongji Cohort
Abstract Educational achievement was related to cardiovascular disease in some western populations, but prospective evidence on the relationship between education and the risk of incident coronary heart disease (CHD) in Asians is scarce. We aimed to explore this association and the potential modifyi...
| Main Authors: | , , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2017-04-01
|
| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-017-00880-8 |
| _version_ | 1818993889367818240 |
|---|---|
| author | Hao Wang Yu Yuan Lulu Song Gaokun Qiu Xuefeng Lai Liangle Yang Yang Xiao Lue Zhou Handong Yang Xiulou Li Chengwei Xu Xiaomin Zhang Mei-an He Tangchun Wu |
| author_facet | Hao Wang Yu Yuan Lulu Song Gaokun Qiu Xuefeng Lai Liangle Yang Yang Xiao Lue Zhou Handong Yang Xiulou Li Chengwei Xu Xiaomin Zhang Mei-an He Tangchun Wu |
| author_sort | Hao Wang |
| collection | DOAJ |
| description | Abstract Educational achievement was related to cardiovascular disease in some western populations, but prospective evidence on the relationship between education and the risk of incident coronary heart disease (CHD) in Asians is scarce. We aimed to explore this association and the potential modifying effect of major CHD risk factors related to education in middle-aged and older Chinese adults. We included 18,551 participants with mean age 62.8 years at baseline between September 2008 and June 2010, and followed the population until October 2013. Cox proportional hazard models and log-binomial regression models were used for multivariate analyses. Compared with participants with low education, the adjusted hazard ratio (HR) and 95% confidence interval (95% CI) for incident CHD in those with high education was 0.89 (95% CI: 0.80, 0.98). In addition, such inverse association between education and the risk of incident CHD was more evident among individuals who were more than 60 years, physically active, overweight, and hypertension. Besides, decreases in the relative index of inequality with high education versus low education were from 0.83 to 0.76 for hypertension, from 0.85 to 0.82 for diabetes. In conclusion, education was inversely associated with the risk of incident CHD among middle-aged and older Chinese adults. |
| first_indexed | 2024-12-20T20:49:13Z |
| format | Article |
| id | doaj.art-7a93dfcdf10c494d8c2a77d93d5f3638 |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-12-20T20:49:13Z |
| publishDate | 2017-04-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-7a93dfcdf10c494d8c2a77d93d5f36382022-12-21T19:26:58ZengNature PortfolioScientific Reports2045-23222017-04-01711810.1038/s41598-017-00880-8Association between education and the risk of incident coronary heart disease among middle-aged and older Chinese: the Dongfeng-Tongji CohortHao Wang0Yu Yuan1Lulu Song2Gaokun Qiu3Xuefeng Lai4Liangle Yang5Yang Xiao6Lue Zhou7Handong Yang8Xiulou Li9Chengwei Xu10Xiaomin Zhang11Mei-an He12Tangchun Wu13Department of Occupational and Environmental Health, Key Laboratory of Environment and Health, Ministry of Education & Ministry of Environmental Protection, State Key Laboratory of Environmental Health (Incubating), School of Public Health, Tongji Medical College, Huazhong University of Science and TechnologyDepartment of Occupational and Environmental Health, Key Laboratory of Environment and Health, Ministry of Education & Ministry of Environmental Protection, State Key Laboratory of Environmental Health (Incubating), School of Public Health, Tongji Medical College, Huazhong University of Science and TechnologyDepartment of Maternal and Child Health, School of Public Health, Tongji Medical College, Huazhong University of Science and TechnologyDepartment of Occupational and Environmental Health, Key Laboratory of Environment and Health, Ministry of Education & Ministry of Environmental Protection, State Key Laboratory of Environmental Health (Incubating), School of Public Health, Tongji Medical College, Huazhong University of Science and TechnologyDepartment of Occupational and Environmental Health, Key Laboratory of Environment and Health, Ministry of Education & Ministry of Environmental Protection, State Key Laboratory of Environmental Health (Incubating), School of Public Health, Tongji Medical College, Huazhong University of Science and TechnologyDepartment of Occupational and Environmental Health, Key Laboratory of Environment and Health, Ministry of Education & Ministry of Environmental Protection, State Key Laboratory of Environmental Health (Incubating), School of Public Health, Tongji Medical College, Huazhong University of Science and TechnologyDepartment of Occupational and Environmental Health, Key Laboratory of Environment and Health, Ministry of Education & Ministry of Environmental Protection, State Key Laboratory of Environmental Health (Incubating), School of Public Health, Tongji Medical College, Huazhong University of Science and TechnologyDepartment of Occupational and Environmental Health, Key Laboratory of Environment and Health, Ministry of Education & Ministry of Environmental Protection, State Key Laboratory of Environmental Health (Incubating), School of Public Health, Tongji Medical College, Huazhong University of Science and TechnologyDongfeng Central Hospital, Dongfeng Motor Corporation and Hubei University of MedicineDongfeng Central Hospital, Dongfeng Motor Corporation and Hubei University of MedicineDongfeng Central Hospital, Dongfeng Motor Corporation and Hubei University of MedicineDepartment of Occupational and Environmental Health, Key Laboratory of Environment and Health, Ministry of Education & Ministry of Environmental Protection, State Key Laboratory of Environmental Health (Incubating), School of Public Health, Tongji Medical College, Huazhong University of Science and TechnologyDepartment of Occupational and Environmental Health, Key Laboratory of Environment and Health, Ministry of Education & Ministry of Environmental Protection, State Key Laboratory of Environmental Health (Incubating), School of Public Health, Tongji Medical College, Huazhong University of Science and TechnologyDepartment of Occupational and Environmental Health, Key Laboratory of Environment and Health, Ministry of Education & Ministry of Environmental Protection, State Key Laboratory of Environmental Health (Incubating), School of Public Health, Tongji Medical College, Huazhong University of Science and TechnologyAbstract Educational achievement was related to cardiovascular disease in some western populations, but prospective evidence on the relationship between education and the risk of incident coronary heart disease (CHD) in Asians is scarce. We aimed to explore this association and the potential modifying effect of major CHD risk factors related to education in middle-aged and older Chinese adults. We included 18,551 participants with mean age 62.8 years at baseline between September 2008 and June 2010, and followed the population until October 2013. Cox proportional hazard models and log-binomial regression models were used for multivariate analyses. Compared with participants with low education, the adjusted hazard ratio (HR) and 95% confidence interval (95% CI) for incident CHD in those with high education was 0.89 (95% CI: 0.80, 0.98). In addition, such inverse association between education and the risk of incident CHD was more evident among individuals who were more than 60 years, physically active, overweight, and hypertension. Besides, decreases in the relative index of inequality with high education versus low education were from 0.83 to 0.76 for hypertension, from 0.85 to 0.82 for diabetes. In conclusion, education was inversely associated with the risk of incident CHD among middle-aged and older Chinese adults.https://doi.org/10.1038/s41598-017-00880-8 |
| spellingShingle | Hao Wang Yu Yuan Lulu Song Gaokun Qiu Xuefeng Lai Liangle Yang Yang Xiao Lue Zhou Handong Yang Xiulou Li Chengwei Xu Xiaomin Zhang Mei-an He Tangchun Wu Association between education and the risk of incident coronary heart disease among middle-aged and older Chinese: the Dongfeng-Tongji Cohort Scientific Reports |
| title | Association between education and the risk of incident coronary heart disease among middle-aged and older Chinese: the Dongfeng-Tongji Cohort |
| title_full | Association between education and the risk of incident coronary heart disease among middle-aged and older Chinese: the Dongfeng-Tongji Cohort |
| title_fullStr | Association between education and the risk of incident coronary heart disease among middle-aged and older Chinese: the Dongfeng-Tongji Cohort |
| title_full_unstemmed | Association between education and the risk of incident coronary heart disease among middle-aged and older Chinese: the Dongfeng-Tongji Cohort |
| title_short | Association between education and the risk of incident coronary heart disease among middle-aged and older Chinese: the Dongfeng-Tongji Cohort |
| title_sort | association between education and the risk of incident coronary heart disease among middle aged and older chinese the dongfeng tongji cohort |
| url | https://doi.org/10.1038/s41598-017-00880-8 |
| work_keys_str_mv | AT haowang associationbetweeneducationandtheriskofincidentcoronaryheartdiseaseamongmiddleagedandolderchinesethedongfengtongjicohort AT yuyuan associationbetweeneducationandtheriskofincidentcoronaryheartdiseaseamongmiddleagedandolderchinesethedongfengtongjicohort AT lulusong associationbetweeneducationandtheriskofincidentcoronaryheartdiseaseamongmiddleagedandolderchinesethedongfengtongjicohort AT gaokunqiu associationbetweeneducationandtheriskofincidentcoronaryheartdiseaseamongmiddleagedandolderchinesethedongfengtongjicohort AT xuefenglai associationbetweeneducationandtheriskofincidentcoronaryheartdiseaseamongmiddleagedandolderchinesethedongfengtongjicohort AT liangleyang associationbetweeneducationandtheriskofincidentcoronaryheartdiseaseamongmiddleagedandolderchinesethedongfengtongjicohort AT yangxiao associationbetweeneducationandtheriskofincidentcoronaryheartdiseaseamongmiddleagedandolderchinesethedongfengtongjicohort AT luezhou associationbetweeneducationandtheriskofincidentcoronaryheartdiseaseamongmiddleagedandolderchinesethedongfengtongjicohort AT handongyang associationbetweeneducationandtheriskofincidentcoronaryheartdiseaseamongmiddleagedandolderchinesethedongfengtongjicohort AT xiulouli associationbetweeneducationandtheriskofincidentcoronaryheartdiseaseamongmiddleagedandolderchinesethedongfengtongjicohort AT chengweixu associationbetweeneducationandtheriskofincidentcoronaryheartdiseaseamongmiddleagedandolderchinesethedongfengtongjicohort AT xiaominzhang associationbetweeneducationandtheriskofincidentcoronaryheartdiseaseamongmiddleagedandolderchinesethedongfengtongjicohort AT meianhe associationbetweeneducationandtheriskofincidentcoronaryheartdiseaseamongmiddleagedandolderchinesethedongfengtongjicohort AT tangchunwu associationbetweeneducationandtheriskofincidentcoronaryheartdiseaseamongmiddleagedandolderchinesethedongfengtongjicohort |