Epithelium-Intrinsic MicroRNAs Contribute to Mucosal Immune Homeostasis by Promoting M-Cell Maturation.

Epithelium-Intrinsic MicroRNAs Contribute to Mucosal Immune Homeostasis by Promoting M-Cell Maturation.

M cells in the follicle-associated epithelium (FAE) of Peyer's patches (PPs) serve as a main portal for external antigens and function as a sentinel in mucosal immune responses. The scarcity of these cells has hampered identification of M cell-specific molecules. Recent efforts have begun to pr...

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Bibliographic Details
Main Authors: Gaku Nakato, Koji Hase, Takao Sato, Shunsuke Kimura, Sayuri Sakakibara, Machiko Sugiyama, Yuuki Obata, Misaho Hanazato, Toshihiko Iwanaga, Hiroshi Ohno
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4773159?pdf=render

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