MiR-185 Targets the DNA Methyltransferases 1 and Regulates Global DNA Methylation in human glioma

MiR-185 Targets the DNA Methyltransferases 1 and Regulates Global DNA Methylation in human glioma

<p>Abstract</p> <p>Background</p> <p>Perturbation of DNA methylation is frequent in cancers and has emerged as an important mechanism involved in tumorigenesis. To determine how DNA methylation is modified in the genome of primary glioma, we used Methyl-DNA immunoprecip...

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Bibliographic Details
Main Authors: Wang Rong, Liu Xiaoping, Xiao Lan, Lu Hongmei, Liu Wei, Zhang Baoxin, Wang Zeyou, Tang Hailin, Zhang Zuping, Li Xiaoling, Wu Minghua, Li Guiyuan
Format: Article
Language:English
Published: BMC 2011-09-01
Series:Molecular Cancer
Subjects:
DNA methylation
MiR-185
Glioma
DNMT1
Online Access:http://www.molecular-cancer.com/content/10/1/124

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