Super resolution microscopy reveals that caveolin-1 is required for spatial organization of CRFB1 and subsequent antiviral signaling in zebrafish.

Super resolution microscopy reveals that caveolin-1 is required for spatial organization of CRFB1 and subsequent antiviral signaling in zebrafish.

Understanding spatial distribution and dynamics of receptors within unperturbed membranes is essential for elucidating their role in antiviral signaling, but conventional studies of detergent-resistant membrane fractions cannot provide this information. Caveolae are integral to numerous signaling pa...

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Bibliographic Details
Main Authors: Kristin A Gabor, Chad R Stevens, Matthew J Pietraszewski, Travis J Gould, Juyoung Shim, Jeffrey A Yoder, Siew Hong Lam, Zhiyuan Gong, Samuel T Hess, Carol H Kim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3706321?pdf=render

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